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Trial · NCT04731727

Treating Corneal Thinning Conditions With CCL Vario Riboflavin (CXL)

NCT04731727, Early phase 1, Not yet recruiting, Kent Wellish MD

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Treating Corneal Thinning Conditions With CCL Vario Riboflavin (CXL). Trials, record NCT04731727. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04731727

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Treating Corneal Thinning Conditions With CCL Vario Riboflavin (CXL)
NCT number
NCT04731727
Status
Not yet recruiting
Phases
Early phase 1
Enrollment
600 participants, estimated
Lead sponsor
Kent Wellish MD
Conditions
Keratoconus, Unstable
Interventions
Riboflavin
First posted
2021-02-01
Last updated
2021-05-25

Source ClinicalTrials.gov

Registered outcomes3

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in Best Corrected Visual AcuityBaseline and 1 yearUse a standard eye chart to determine changes in the subject's best Visual Acuity (with glasses or contact) performed by research staff
PrimaryChange in Uncorrected Visual AcuityBaseline and 1 yearUse a standard eye chart to determine changes in the subject's best Visual Acuity (without glasses or contact) performed by clinic technician
PrimaryOccurrence of Adverse EventsThrough study completion, an average of 1 yearSurgeon notes any occurrence of adverse events related to the treatment

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04731727

GET https://conductscience.org/api/trials/v1/NCT04731727/registered