Trial · NCT04744090
Roflumilast as add-on Therapy in Early Cases of ARDS
NCT04744090, Phase 2, Completed, Cairo University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Roflumilast as add-on Therapy in Early Cases of ARDS. Trials, record NCT04744090. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04744090
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Roflumilast as add-on Therapy in Early Cases of ARDS
- NCT number
- NCT04744090
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 76 participants, actual
- Lead sponsor
- Cairo University
- Conditions
- Respiratory Distress Syndrome, Adult
- Interventions
- Roflumilast, Placebo
- First posted
- 2021-02-08
- Last updated
- 2022-04-04
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in clinical picture (two-point reduction in patient's admission status) | Follow up for up to 28 days. | Defined as a two-point reduction in patient's admission status on a five-point ordinal scale, or live discharge from hospital whichever came first. • The five-point ordinal scale is as follow: 1. Discharge 2. Hospital admission, not requiring oxygen supplement 3. Hospital admission, requiring oxygen supplement 4. Hospital admission for high flow oxygen therapy or non-invasive mechanical ventilation 5. Hospital admission for mechanical ventilation or extracorporeal membrane oxygenation |
| Secondary | Evaluation of change in systemic inflammatory parameters, including ferritin. | Weekly assessment (baseline, day7, day14, at the end) for up to 28 days. | |
| Secondary | Evaluation of change in systemic inflammatory parameters, including CRP. | Weekly assessment (baseline, day7, day14, at the end) for up to 28 days. | |
| Secondary | Evaluation of change in systemic inflammatory parameters, including LDH. | Weekly assessment (baseline, day7, day14, at the end) for up to 28 days. | |
| Secondary | Total hospital stay. | Follow up for up to 28 days. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04744090
GET https://conductscience.org/api/trials/v1/NCT04744090/registered