Exercise the Mind and Brain. A Multimodal Intervention in Stroke
NCT04759950, Not applicable, Completed, University of Barcelona
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Exercise the Mind and Brain. A Multimodal Intervention in Stroke | ClinicalTrials.gov |
| NCT number | NCT04759950 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 141 participants, actual | ClinicalTrials.gov |
| Lead sponsor | University of Barcelona | ClinicalTrials.gov |
| Conditions | Stroke | ClinicalTrials.gov |
| Interventions | Multicomponent Physical Activity Program, Mindfulness-Based Stress Reduction Program, Computerized Cognitive Training | ClinicalTrials.gov |
| First posted | 2021-02-18 | ClinicalTrials.gov |
| Last updated | 2022-03-02 | ClinicalTrials.gov |
Registered outcomes 23
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change in immediate verbal attention after receiving treatment | 3 months (at baseline, 3 months from baseline) | Forward Digit Span (WAIS III) | ClinicalTrials.gov |
| Primary | Change in verbal digit working memory after receiving treatment | 3 months (at baseline, 3 months from baseline) | Backward Digit Span (WAIS III) | ClinicalTrials.gov |
| Primary | Change in verbal memory after receiving treatment | 3 months (at baseline, 3 months from baseline) | Rey Auditory Learning Test | ClinicalTrials.gov |
| Primary | Change in visual memory after receiving treatment | 3 months (at baseline, 3 months from baseline) | Rey's Complex Figure Test | ClinicalTrials.gov |
| Primary | Change in executive function, verbal fluency after receiving treatment | 3 months (at baseline, 3 months from baseline) | Phonetic Fluency is measured using the Controlled Oral Word Association Test, spanish adaptation, and semantic fluency test using the category Animal | ClinicalTrials.gov |
| Primary | Change in executive function, inhibition after receiving treatment | 3 months (at baseline, 3 months from baseline) | Stroop Test | ClinicalTrials.gov |
| Primary | Change in executive function, set-switching task after receiving treatment | 3 months (at baseline, 3 months from baseline) | Trail Making Test | ClinicalTrials.gov |
| Primary | Change in language, naming after receiving treatment | 3 months (at baseline, 3 months from baseline) | Boston naming Test | ClinicalTrials.gov |
| Secondary | Changes in psychological distress | 3 months (at baseline, 3 months from baseline) | Clinical Outcomes in Routine Evaluation (CORE-OM) | ClinicalTrials.gov |
| Secondary | Changes in depression and anxiety | 3 months (at baseline, 3 months from baseline) | Depression Anxiety Stress Scale (DASS-21) | ClinicalTrials.gov |
| Secondary | Changes in wellbeing | 3 months (at baseline, 3 months from baseline) | Ryff Scales of Psychological Wellbeing. | ClinicalTrials.gov |
| Secondary | Changes in Mindfulness | 3 months (at baseline, 3 months from baseline) | Mindful Attention Awareness Scale (MAAS) | ClinicalTrials.gov |
| Secondary | Changes in White matter integrity | 3 months (at baseline, 3 months from baseline) | White matter integrity: tractography | ClinicalTrials.gov |
| Secondary | Changes in Resting-state connectivity | 3 months (at baseline, 3 months from baseline) | Resting state brain activity using fMRI | ClinicalTrials.gov |
| Secondary | Changes in brain volumetry | 3 months (at baseline, 3 months from baseline) | Grey and white matter volume measured by MRI | ClinicalTrials.gov |
| Secondary | Molecular changes: growth factors (BDNF, SDF1-a, VEGF-A, IGF-1, and NGF), cortisol, protein C reactive, IL-6 and homocysteine levels | 3 months (at baseline, 3 months from baseline) | Quantification of different biomarkers from blood samples. | ClinicalTrials.gov |
| Secondary | Changes in Microbiota data | 3 months (at baseline, 3 months from baseline) | Bacterial composition of stool samples in terms of relative abundance | ClinicalTrials.gov |
| Secondary | Changes in Sleep | 3 months (at baseline, 3 months from baseline) | Pittsburgh Sleep Quality Index (PSQI) | ClinicalTrials.gov |
| Secondary | Changes in Fitness | 3 months (at baseline, 3 months from baseline) | Senior Fitness Test (SFT) | ClinicalTrials.gov |
| Secondary | Changes in stroke specific quality of life | 3 months (at baseline, 3 months from baseline) | Stroke-specific Quality of Life Scale (ECVI-38) | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 2
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 8
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Category Fluency | Primary outcome | ConductCognition |
| Complex Figure Copy and Recall | Primary outcome | ConductCognition |
| Digit Span Test | Primary outcome | ConductCognition |
| Picture Naming Test | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Trail Making Test A | Primary outcome | ConductCognition |
| Trail Making Test B | Primary outcome | ConductCognition |
| Verbal Fluency | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)