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Trial · NCT04762277

Results by group24

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percent Change From Baseline in Total Abscess and Inflammatory Nodule Count at Week 12Placebo-34.7Standard Error 11.1percent change
Percent Change From Baseline in Total Abscess and Inflammatory Nodule Count at Week 12Spesolimab-38.8Standard Error 7.5percent change
Percent Change From Baseline in Draining Fistula Count at Week 12Placebo56.6Standard Deviation 23.0percent change
Percent Change From Baseline in Draining Fistula Count at Week 12Spesolimab-40.1Standard Deviation 16.8percent change
Achievement of Hidradenitis Suppurativa Clinical Response (HiSCR) at Week 12Placebo0.176proportion of patients
Achievement of Hidradenitis Suppurativa Clinical Response (HiSCR) at Week 12Spesolimab0.314proportion of patients
Absolute Change From Baseline in International Hidradenitis Suppurativa Severity Score System (IHS4) Value at Week 12Placebo4.9Standard Error 4.7units on a scale
Absolute Change From Baseline in International Hidradenitis Suppurativa Severity Score System (IHS4) Value at Week 12Spesolimab-9.0Standard Error 3.2units on a scale
Absolute Change From Baseline in Hidradenitis Suppurativa Area and Severity Index (HASI) Score at Week 12Placebo-3.8Standard Error 6.9units on a scale
Absolute Change From Baseline in Hidradenitis Suppurativa Area and Severity Index (HASI) Score at Week 12Spesolimab-23.6Standard Error 4.7units on a scale
Achievement of Hidradenitis Suppurativa Physician Global Assessment (HS-PGA) Score of 0 or 1 at Week 12Placebo0.000proportion of patients
Achievement of Hidradenitis Suppurativa Physician Global Assessment (HS-PGA) Score of 0 or 1 at Week 12Spesolimab0.057proportion of patients
Achievement of at Least 30% Reduction From Baseline in Numerical Rating Scale (NRS30) in Patient's Global Assessment of HS Pain at Week 12Placebo0.059proportion of patients
Achievement of at Least 30% Reduction From Baseline in Numerical Rating Scale (NRS30) in Patient's Global Assessment of HS Pain at Week 12Spesolimab0.229proportion of patients
Occurrence of Complete Elimination of Draining Fistulas at Week 12Placebo0.067proportion of patients
Occurrence of Complete Elimination of Draining Fistulas at Week 12Spesolimab0.250proportion of patients
Occurrence of at Least One Flare at Week 12Placebo0.176proportion of patients
Occurrence of at Least One Flare at Week 12Spesolimab0.086proportion of patients
Absolute Change From Baseline in Dermatology Life Quality Index (DLQI) Score at Week 12Placebo-2.8Standard Error 1.8units on a scale
Absolute Change From Baseline in Dermatology Life Quality Index (DLQI) Score at Week 12Spesolimab-2.8Standard Error 1.2units on a scale

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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