Trial · NCT04768166
Testing Miglustat Administration in Subjects With Spastic Paraplegia 11
NCT04768166, Phase 2, Completed, IRCCS Fondazione Stella Maris
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Testing Miglustat Administration in Subjects With Spastic Paraplegia 11. Trials, record NCT04768166. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04768166
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Testing Miglustat Administration in Subjects With Spastic Paraplegia 11
- NCT number
- NCT04768166
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 10 participants, actual
- Lead sponsor
- IRCCS Fondazione Stella Maris
- Conditions
- Hereditary Spastic Paraparesis
- Interventions
- Miglustat 100 MG
- First posted
- 2021-02-24
- Last updated
- 2022-04-11
- Other registries' IDs
- eudract:2019-002827-14
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 1-Changes from baseline blood tests at 24 weeks 2-Changes from baseline neurophysiological tests at 24 weeks 3-Report of severe adverse events | At baseline, 24 weeks | routine blood test |
| Secondary | Changes from baseline GM2/GM3 levels at 24 weeks | At baseline, 24 weeks | lipid assessments |
| Secondary | Assess changes in the scores of the Spastic Paraplegia Rating Scale (SPRS) at 24 weeks | At baseline, 24 weeks | SPRS rates disease severity (0-52) with lower numbers indicating less impairement |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers5
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04768166
GET https://conductscience.org/api/trials/v1/NCT04768166/registered