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Trial · NCT04770779

Results by group77

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Double-blind Period: Percentage of Participants Who Achieved Transfusion Reduction Response (TRR)Mitapivat30.4percentage of participants
Double-blind Period: Percentage of Participants Who Achieved Transfusion Reduction Response (TRR)Placebo12.6percentage of participants
Double-blind Period: Percentage of Participants Who Achieved TRR2Mitapivat13.5percentage of participants
Double-blind Period: Percentage of Participants Who Achieved TRR2Placebo2.3percentage of participants
Double-blind Period: Percentage of Participants Who Achieved TRR3Mitapivat14.6percentage of participants
Double-blind Period: Percentage of Participants Who Achieved TRR3Placebo1.1percentage of participants
Double-blind Period: Percentage of Participants Who Achieved TRR4Mitapivat7.6percentage of participants
Double-blind Period: Percentage of Participants Who Achieved TRR4Placebo1.1percentage of participants
Double-blind Period: Percent Change From Baseline in Transfused RBC UnitsMitapivat10.96Standard Error 2.149percent change
Double-blind Period: Percent Change From Baseline in Transfused RBC UnitsPlacebo3.32Standard Error 2.846percent change
Double-blind Period: Percentage of Participants Who Achieved Transfusion-IndependenceMitapivat9.9percentage of participants
Double-blind Period: Percentage of Participants Who Achieved Transfusion-IndependencePlacebo1.1percentage of participants
Double-blind Period: Change From Baseline in Iron LevelsMitapivat-4.57Standard Error 0.949micromoles per liter (µmol/L)
Double-blind Period: Change From Baseline in Iron LevelsPlacebo2.06Standard Error 1.280micromoles per liter (µmol/L)
Double-blind Period: Change From Baseline in Serum Ferritin LevelsMitapivat45.3Standard Error 88.90micrograms per liter (µg/L)
Double-blind Period: Change From Baseline in Serum Ferritin LevelsPlacebo76.3Standard Error 119.84micrograms per liter (µg/L)
Double-blind Period: Change From Baseline in Total Iron Binding CapacityMitapivat-21.80Standard Error 3.597µmol/L
Double-blind Period: Change From Baseline in Total Iron Binding CapacityPlacebo-1.23Standard Error 5.053µmol/L
Double-blind Period: Change From Baseline in Transferrin Saturation (TSAT) LevelsMitapivat0.079Standard Error 0.0261Ratio
Double-blind Period: Change From Baseline in Transferrin Saturation (TSAT) LevelsPlacebo-0.013Standard Error 0.0371Ratio

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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