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Trial · NCT04773600

Results by group22

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Achievement of Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD) Success at Week 4Roflumilast Cream 0.15%28.9percentage of participants
Achievement of Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD) Success at Week 4Vehicle Cream12.0percentage of participants
Achievement of vIGA-AD Success at Week 4 in Participants With Moderate Baseline ScoresRoflumilast Cream 0.15%32.9percentage of participants
Achievement of vIGA-AD Success at Week 4 in Participants With Moderate Baseline ScoresVehicle Cream13.1percentage of participants
vIGA-AD Success at Week 2Roflumilast Cream 0.15%17.7percentage of participants
vIGA-AD Success at Week 2Vehicle Cream5.3percentage of participants
vIGA-AD Success at Week 1Roflumilast Cream 0.15%5.9percentage of participants
vIGA-AD Success at Week 1Vehicle Cream3.1percentage of participants
Achievement of a 4-point Reduction at Week 4 in the Average, Weekly Worst Itch Numeric Rating Scale (WI-NRS) in Participants With Baseline WI-NRS Score ≥4Roflumilast Cream 0.15%30.295% Confidence Interval 24.77 to 36.31percentage of participants
Achievement of a 4-point Reduction at Week 4 in the Average, Weekly Worst Itch Numeric Rating Scale (WI-NRS) in Participants With Baseline WI-NRS Score ≥4Vehicle Cream12.495% Confidence Interval 7.77 to 19.26percentage of participants
Achievement of a 4-point Reduction at Week 2 in the WI-NRS in Participants With Baseline WI-NRS Score ≥4Roflumilast Cream 0.15%22.395% Confidence Interval 17.66 to 27.82percentage of participants
Achievement of a 4-point Reduction at Week 2 in the WI-NRS in Participants With Baseline WI-NRS Score ≥4Vehicle Cream6.995% Confidence Interval 3.66 to 12.56percentage of participants
Achievement of a 4-point Reduction at Week 1 in the WI-NRS in Participants With Baseline WI-NRS Score ≥4Roflumilast Cream 0.15%11.295% Confidence Interval 7.89 to 15.57percentage of participants
Achievement of a 4-point Reduction at Week 1 in the WI-NRS in Participants With Baseline WI-NRS Score ≥4Vehicle Cream1.695% Confidence Interval 0.44 to 5.58percentage of participants
Achievement of ≥75% Decrease From Baseline at Week 4 in the Eczema Area and Severity Index (EASI-75)Roflumilast Cream 0.15%42.095% Confidence Interval 37.45 to 46.72percentage of participants
Achievement of ≥75% Decrease From Baseline at Week 4 in the Eczema Area and Severity Index (EASI-75)Vehicle Cream19.795% Confidence Interval 15.04 to 25.44percentage of participants
Achievement of vIGA-AD Score of 'Clear' or 'Almost Clear' at Week 4Roflumilast Cream 0.15%39.0percentage of participants
Achievement of vIGA-AD Score of 'Clear' or 'Almost Clear' at Week 4Vehicle Cream16.9percentage of participants
Achievement of vIGA-AD Score of 'Clear' or 'Almost Clear' at Week 2Roflumilast Cream 0.15%27.6percentage of participants
Achievement of vIGA-AD Score of 'Clear' or 'Almost Clear' at Week 2Vehicle Cream10.7percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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