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Trial · NCT04777331

Results by group36

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
DBT Period: Time to Confirmed Motor Progression Event Assessed by Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part IIIDBT Period: Placebo49.795% Confidence Interval 40.1 to 58.1weeks
DBT Period: Time to Confirmed Motor Progression Event Assessed by Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part IIIDBT Period: Prasinezumab61.195% Confidence Interval 52.3 to 71.9weeks
DBT Period: Time-to-worsening of Participant's Motor Function as Reported by the Participant in the Presence of a Confirmed Motor Progression EventDBT Period: Placebo88.395% Confidence Interval 62.7 to 105.1weeks
DBT Period: Time-to-worsening of Participant's Motor Function as Reported by the Participant in the Presence of a Confirmed Motor Progression EventDBT Period: Prasinezumab112.195% Confidence Interval 81.1 to NAweeks
DBT Period: Time to Meaningful Worsening in Participant Global Impression of Change (PGI-C) Overall Disease SubscaleDBT Period: Placebo36.195% Confidence Interval 29.9 to 42.1weeks
DBT Period: Time to Meaningful Worsening in Participant Global Impression of Change (PGI-C) Overall Disease SubscaleDBT Period: Prasinezumab44.495% Confidence Interval 38.1 to 52.1weeks
DBT Period: Time to Meaningful Worsening in Clinician Global Impression of Change (CGI-C) Overall Disease SubscaleDBT Period: Placebo52.195% Confidence Interval 44.1 to 59.9weeks
DBT Period: Time to Meaningful Worsening in Clinician Global Impression of Change (CGI-C) Overall Disease SubscaleDBT Period: Prasinezumab60.695% Confidence Interval 56.1 to 67.3weeks
DBT Period: Time to Onset of Motor Complications as Assessed Through MDS-UPDRS Part IVDBT Period: Placebo91.195% Confidence Interval 77.0 to 107.6weeks
DBT Period: Time to Onset of Motor Complications as Assessed Through MDS-UPDRS Part IVDBT Period: Prasinezumab100.195% Confidence Interval 81.0 to 117.1weeks
DBT Period: Change in Motor Function From Baseline to Week 76, as Measured by the MDS-UPDRS Part III ScoreDBT Period: Placebo4.00Standard Error 0.592Units on a scale
DBT Period: Change in Motor Function From Baseline to Week 76, as Measured by the MDS-UPDRS Part III ScoreDBT Period: Prasinezumab3.61Standard Error 0.597Units on a scale
DBT Period: Change in Bradykinesia and Rigidity From Baseline to Week 76, as Measured by the MDS-UPDRS Part III Bradykinesia and Rigidity SubscoreDBT Period: Placebo2.77Standard Error 0.476Units on a scale
DBT Period: Change in Bradykinesia and Rigidity From Baseline to Week 76, as Measured by the MDS-UPDRS Part III Bradykinesia and Rigidity SubscoreDBT Period: Prasinezumab2.85Standard Error 0.479Units on a scale
DBT Period: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)DBT Period: PlaceboAEs260Participants
DBT Period: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)DBT Period: PrasinezumabAEs267Participants
DBT Period: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)DBT Period: PlaceboSAEs34Participants
DBT Period: Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)DBT Period: PrasinezumabSAEs34Participants
DBT Period: Number of Participants With Adverse Events of Special Interest (AESI)DBT Period: Placebo0Participants
DBT Period: Number of Participants With Adverse Events of Special Interest (AESI)DBT Period: Prasinezumab0Participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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