Trial · NCT04820751
Cyproheptadine in Severe COVID-19 : A Unblinded Randomized Trial
NCT04820751, Phase 3, Unknown, Ciusss de L'Est de l'Île de Montréal
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cyproheptadine in Severe COVID-19 : A Unblinded Randomized Trial. Trials, record NCT04820751. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04820751
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cyproheptadine in Severe COVID-19 : A Unblinded Randomized Trial
- NCT number
- NCT04820751
- Status
- Unknown
- Phases
- Phase 3
- Enrollment
- 200 participants, estimated
- Lead sponsor
- Ciusss de L'Est de l'Île de Montréal
- Conditions
- Viral Pneumonia, Serotonin Syndrome, Platelet Dysfunction
- Interventions
- Cyproheptadine Hydrochloride 4 MG
- First posted
- 2021-03-29
- Last updated
- 2021-04-02
Source ClinicalTrials.gov
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Length of hospitalization | Through study completion, an average of 1 year | |
| Primary | Need mechanical ventilation (Non invasive or Invasive) | Through study completion, an average of 1 year | |
| Secondary | Death | Day 28 | |
| Secondary | Length of hospitalization in the intensive care unit | Through study completion, an average of 1 year | |
| Secondary | Duration of mechanical ventilation | Through study completion, an average of 1 year | |
| Secondary | SOFA Score | At Day 1,3,5,7,10 after randomization | Sequential Organ Failure Min Score 0-Max score 24 Higher scores mean a worse outcome |
| Secondary | Heart rate | At Day 1,3,5,7,10 after randomization | |
| Secondary | Respiratory Rate | At Day 1,3,5,7,10 after randomization | |
| Secondary | Spo2/FiO2 and ROX ratio | At Day 1,3,5,7,10 after randomization | |
| Secondary | CRP level | At Day 1,3,5,7,10 after randomization |
1 to 10 of 13Source ClinicalTrials.gov
See all 13 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04820751
GET https://conductscience.org/api/trials/v1/NCT04820751/registered