The Effect of Probiotic Supplementation on Cognitive and Emotional Functions in Healthy Elderly Subjects
NCT04828421, Not applicable, Completed, Universidad de Almeria
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | The Effect of Probiotic Supplementation on Cognitive and Emotional Functions in Healthy Elderly Subjects | ClinicalTrials.gov |
| NCT number | NCT04828421 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 36 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Universidad de Almeria | ClinicalTrials.gov |
| Conditions | Healthy | ClinicalTrials.gov |
| Interventions | Lactobacillus rhamnosus and Bifidobacterium lactis, Placebo | ClinicalTrials.gov |
| First posted | 2021-04-02 | ClinicalTrials.gov |
| Last updated | 2022-06-01 | ClinicalTrials.gov |
Registered outcomes 18
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change from Baseline Anxiety at 10 weeks | Before and after treatment (10 weeks) | The State-Trait Anxiety Inventory. Score range: 20-80 | ClinicalTrials.gov |
| Primary | Change from Baseline Depression at 10 weeks | Before and after treatment (10 weeks) | The Beck Depression Inventory. Score range: 0-63. | ClinicalTrials.gov |
| Primary | Change from Baseline General Cognitive Status at 10 weeks | Before and after treatment (10 weeks) | Mini-Mental State Examination. Score range: 0-35 | ClinicalTrials.gov |
| Primary | Change from Baseline Working Memory at 10 weeks | Before and after treatment (10 weeks) | Digits task, Corsi task | ClinicalTrials.gov |
| Primary | Change from Baseline Planning Ability at 10 weeks | Before and after treatment (10 weeks) | Tower of London test | ClinicalTrials.gov |
| Primary | Change from Baseline Problem-solving ability at 10 weeks | Before and after treatment (10 weeks) | Wisconsin Card Sorting test | ClinicalTrials.gov |
| Primary | Change from Baseline Selective attention, cognitive flexibility and response inhibition at 10 weeks | Before and after treatment (10 weeks) | Stroop task | ClinicalTrials.gov |
| Primary | Change from Baseline Visual Attention at 10 weeks | Before and after treatment (10 weeks) | Trail Making Test | ClinicalTrials.gov |
| Primary | Change from Baseline Motor impulsivity or inhibitory response at 10 weeks | Before and after treatment (10 weeks) | Go/No-Go task | ClinicalTrials.gov |
| Primary | Change from Baseline Choice impulsivity or impulsive decision-making at 10 weeks | Before and after treatment (10 weeks) | Iowa Gambling Task | ClinicalTrials.gov |
| Secondary | Change from Baseline Food Habits at 10 weeks | Before and after treatment (10 weeks) | "24-hour recall" questionnaire | ClinicalTrials.gov |
| Secondary | Change from Baseline Alcohol Use at 10 weeks | Before and after treatment (10 weeks) | The Alcohol Use Disorders Identification Test. Score range: 0-40 | ClinicalTrials.gov |
| Secondary | Change from Baseline Body Composition at 10 weeks | Before and after treatment (10 weeks) | Fat mass. Body fat mass. Fat-free mass. Total body water. | ClinicalTrials.gov |
| Secondary | Change from Baseline Physical Activity at 10 weeks | Before and after treatment (10 weeks) | International Physical Activity Questionnaire | ClinicalTrials.gov |
| Secondary | Change from Baseline Stool Consistency at 10 weeks | Before and after treatment (10 weeks) | The Bristol Scale | ClinicalTrials.gov |
| Secondary | Change from Baseline Sleep Quality at 10 weeks | Before and after treatment (10 weeks) | The Pittsburgh Sleep Quality Index Questionnaire. Score range: 0-21 | ClinicalTrials.gov |
| Secondary | Change from Baseline Perceived Stress at 10 weeks | Before and after treatment (10 weeks) | Perceived Stress Questionnaire. Score range: 0-1 | ClinicalTrials.gov |
| Secondary | Change from Baseline Gastrointestinal Symptom at 10 weeks | Before and after treatment (10 weeks) | Gastrointestinal Symptom Rating Scale | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 38935259 | DERIVED | PubMed |
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 8
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Card Sorting Test (Berg) | Primary outcome | ConductCognition |
| Corsi Block-Tapping Test | Primary outcome | ConductCognition |
| Go/No-Go Task | Primary outcome | ConductCognition |
| Iowa Gambling Lite | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Tower Planning | Primary outcome | ConductCognition |
| Trail Making Test A | Primary outcome | ConductCognition |
| Trail Making Test B | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)