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Trial · NCT04842292

Nebulized Heparin for COVID19-associated Acute Respiratory Failure

NCT04842292, Phase 2, Terminated, Brittany Bissell; results first posted 2022-10-18

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Nebulized Heparin for COVID19-associated Acute Respiratory Failure. Trials, record NCT04842292. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04842292

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Nebulized Heparin for COVID19-associated Acute Respiratory Failure
NCT number
NCT04842292
Status
Terminated
Phases
Phase 2
Enrollment
2 participants, actual
Lead sponsor
Brittany Bissell
Conditions
Covid19
Interventions
Heparin, Placebo
First posted
2021-04-13
Last updated
2022-10-18
Results first posted
2022-10-18

Source ClinicalTrials.gov

Registered outcomes3

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryMean PaO2/FiO2 RatioWithin the first 10 days of ICU stay or up until ICU discharge, whichever occurs first
SecondaryClinically Significant BleedingUp to discharge or 3 months following enrollment, whichever occurs first
SecondaryIncidence of Venous ThromboembolismUp to discharge or 3 months following enrollment, whichever occurs first

Outcomes3

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARYMean PaO2/FiO2 RatioWithin the first 10 days of ICU stay or up until ICU discharge, whichever occurs firstTwo participants were enrolled in this study. Due to the possibility that participants could reasonably be identified due to low enrollment, data cannot be presented.units on a scaleMEAN
SECONDARYClinically Significant BleedingUp to discharge or 3 months following enrollment, whichever occurs firstTwo participants were enrolled in this study. Due to the possibility that participants could reasonably be identified due to low enrollment, data cannot be presented.units on a scaleMEAN
SECONDARYIncidence of Venous ThromboembolismUp to discharge or 3 months following enrollment, whichever occurs firstTwo participants were enrolled in this study. Due to the possibility that participants could reasonably be identified due to low enrollment, data cannot be presented.IncidenceNUMBER

Results by group3

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Mean PaO2/FiO2 RatioParticipantsNAStandard Deviation NAunits on a scale
Clinically Significant BleedingParticipantsNAStandard Deviation NAunits on a scale
Incidence of Venous ThromboembolismParticipantsNAIncidence

Participant flow3

How many started, completed or left each group, period by period.

PeriodMilestoneGroupParticipantsUnits counted
Overall StudySTARTEDParticipants2
Overall StudyCOMPLETEDParticipants2
Overall StudyNOT COMPLETEDParticipants0

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals3

The totals the trial posted for each group.

TotalGroupAffectedAt risk
Total, all-cause mortalityParticipants12
Total, other adverse eventsParticipants02
Total, serious adverse eventsParticipants02

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04842292

GET https://conductscience.org/api/trials/v1/NCT04842292/registered