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Trial of PDE4 Inhibition With Roflumilast for the Management of Atopic Dermatitis (Integument-PED)
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Trial · NCT04845620

Results by group16

Each measurement the trial posted, group by group, in the words and numbers it posted.

1 to 16 of 16

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OutcomeGroupCategoryValueSpreadUnits
Achievement of Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD) Success at Week 4Roflumilast Cream 0.05%25.497.5% Confidence Interval 20.95 to 30.34percentage of participants
Achievement of Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD) Success at Week 4Vehicle Cream10.797.5% Confidence Interval 6.77 to 16.45percentage of participants
Achievement of vIGA-AD Success at Week 4 in Participants With 'Moderate' Baseline vIGA-ADRoflumilast Cream 0.05%27.797.5% Confidence Interval 22.55 to 33.62percentage of participants
Achievement of vIGA-AD Success at Week 4 in Participants With 'Moderate' Baseline vIGA-ADVehicle Cream11.097.5% Confidence Interval 6.67 to 17.73percentage of participants
Achievement of 75% Reduction in the Eczema Area and Severity Index (EASI-75) at Week 4 In Participants With 'Moderate' Baseline vIGARoflumilast Cream 0.05%39.497.5% Confidence Interval 34.21 to 44.81percentage of participants
Achievement of 75% Reduction in the Eczema Area and Severity Index (EASI-75) at Week 4 In Participants With 'Moderate' Baseline vIGAVehicle Cream20.697.5% Confidence Interval 15.06 to 27.55percentage of participants
Achievement of vIGA-AD Score of 'Clear' or 'Almost Clear'Roflumilast Cream 0.05%35.497.5% Confidence Interval 30.39 to 40.66percentage of participants
Achievement of vIGA-AD Score of 'Clear' or 'Almost Clear'Vehicle Cream14.697.5% Confidence Interval 9.94 to 20.86percentage of participants
Achievement of vIGA-AD Success at Week 2Roflumilast Cream 0.05%21.297.5% Confidence Interval 17.13 to 25.98percentage of participants
Achievement of vIGA-AD Success at Week 2Vehicle Cream6.897.5% Confidence Interval 3.85 to 11.88percentage of participants
Achievement of vIGA-AD Success at Week 1Roflumilast Cream 0.05%9.497.5% Confidence Interval 6.72 to 13.02percentage of participants
Achievement of vIGA-AD Success at Week 1Vehicle Cream0.997.5% Confidence Interval 0.22 to 3.88percentage of participants
Achievement of vIGA-AD of 'Clear' or 'Almost Clear' at Week 2Roflumilast Cream 0.05%30.497.5% Confidence Interval 25.67 to 35.58percentage of participants
Achievement of vIGA-AD of 'Clear' or 'Almost Clear' at Week 2Vehicle Cream10.697.5% Confidence Interval 6.74 to 16.42percentage of participants
Achievement of vIGA-AD of 'Clear' or 'Almost Clear' at Week 1Roflumilast Cream 0.05%17.0097.5% Confidence Interval 13.32 to 21.37percentage of participants
Achievement of vIGA-AD of 'Clear' or 'Almost Clear' at Week 1Vehicle Cream3.797.5% Confidence Interval 1.73 to 7.83percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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