Trial · NCT04850885
Efficacy of Dexamethasone or Adrenaline in Inferior Alveolar Nerve Block
NCT04850885, Phase 3, Completed, Tribhuvan University, Nepal
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy of Dexamethasone or Adrenaline in Inferior Alveolar Nerve Block. Trials, record NCT04850885. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04850885
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy of Dexamethasone or Adrenaline in Inferior Alveolar Nerve Block
- NCT number
- NCT04850885
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 83 participants, actual
- Lead sponsor
- Tribhuvan University, Nepal
- Conditions
- Oral Surgical Procedure
- Interventions
- inj dexamethasone 4mg/ml and inj lignocaine 20mg/ml
- First posted
- 2021-04-20
- Last updated
- 2021-04-22
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | onset time and duration of anaesthesia. | one week post operative | Postoperative pain is rated on a 10 cm visual analogue scale (VAS) anchored by the verbal description "no pain" (0) and "very severe pain (9)" at every half an hourly up to 24 hours. When the patients began to experience moderate pain (VAS 4-5); it was considered that the anaesthetic effect of the test drugs was terminated. Then patient instructed to take analgesic only prescribed in the researcher. They were asked to record the time every time up to 7 days postoperatively. The nerve block was assessed objectively every two minute time interval (2, 4, 6, 8, 10 and 15 minute) with the application of cold sprit swabs/ice pack in the lower lip and by the response to atraumatic prick with the blunt instrument in a buccal and lingual mucoperiosteum in relation to 1st molar and canine teeth. The time of complete nerve block was achieved before starting the surgical procedure. T |
| Secondary | post operative facial edema | one week post operative | A surgical outcome facial swelling (edema) and trismus were determined by measuring change in facial contour and inability in mouth opening respectively. Clinical measurements of maximum interincisal distance and facial contours were measured at preoperative day (baseline) and postoperatively days (2nd and 7th day). The facial contour was measured by flexible tape from the tragus to pogonian (Figure ). |
| Secondary | trismus | one week post operative | Intercessor distance was measured between upper and lower central incisors after asking the patient to open the mouth fully with the help of a digital vernier calliper. The examiner was the same one who assessed them preoperatively. Facial oedema and trismus were recorded as the differences between postoperative and preoperative (baseline) values at these appointments. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04850885
GET https://conductscience.org/api/trials/v1/NCT04850885/registered