Trial · NCT04860011
DAPAgliflozin Versus Thiazide Diuretic in Patients With Heart Failure and Diuretic RESISTance
NCT04860011, Phase 3, Unknown, NHS Greater Glasgow and Clyde
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. DAPAgliflozin Versus Thiazide Diuretic in Patients With Heart Failure and Diuretic RESISTance. Trials, record NCT04860011. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04860011
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- DAPAgliflozin Versus Thiazide Diuretic in Patients With Heart Failure and Diuretic RESISTance
- NCT number
- NCT04860011
- Status
- Unknown
- Phases
- Phase 3
- Enrollment
- 61 participants, actual
- Lead sponsor
- NHS Greater Glasgow and Clyde
- Conditions
- Heart Failure
- Interventions
- Dapagliflozin 10 MG Oral Tablet, Metolazone Tablets
- First posted
- 2021-04-26
- Last updated
- 2023-04-10
Source ClinicalTrials.gov
Registered outcomes60
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Diuretic effect | from randomisation to 48 hours | Diuretic effect, as assessed by mean change in weight |
| Primary | Diuretic effect | from randomisation to 72 hours | Diuretic effect, as assessed by mean change in weight |
| Primary | Diuretic effect | from randomisation to 96 hours | Diuretic effect, as assessed by mean change in weight |
| Secondary | Change in congestion measured by ultrasound | from randomisation to 48 hours | Change in congestion, assessed using lung ultrasound as a measure of the sum of B-lines across 8 zones |
| Secondary | Change in congestion measured by ultrasound | from randomisation to 72 hours | Change in congestion, assessed using lung ultrasound as a measure of the sum of B-lines across 8 zones |
| Secondary | Change in congestion measured by ultrasound | from randomisation to 96 hours | Change in congestion, assessed using lung ultrasound as a measure of the sum of B-lines across 8 zones |
| Secondary | Loop diuretic efficiency | from randomisation to 48 hours | Loop diuretic efficiency will be defined as weight loss in kilograms divided by furosemide equivalents in milligrams. |
| Secondary | Loop diuretic efficiency | from randomisation to 72 hours | Loop diuretic efficiency will be defined as weight loss in kilograms divided by furosemide equivalents in milligrams. |
| Secondary | Loop diuretic efficiency | from randomisation to 96 hours | Loop diuretic efficiency will be defined as weight loss in kilograms divided by furosemide equivalents in milligrams. |
| Secondary | Change in ADVOR clinical congestion score | from randomisation to 48 hours | Change in ADVOR clinical congestion score will be measured on a scale of 0 to 10 with 0 being the least congested |
1 to 10 of 60Source ClinicalTrials.gov
See all 60 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 37210742 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04860011
GET https://conductscience.org/api/trials/v1/NCT04860011/registered?page=2