Trial · NCT04915365
Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders With COPD Traveling to High Altitude
NCT04915365, Phase 3, Unknown, University of Zurich
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders With COPD Traveling to High Altitude. Trials, record NCT04915365. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04915365
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Acetazolamide on Right Heart Function at Rest in Lowlanders With COPD Traveling to High Altitude
- NCT number
- NCT04915365
- Status
- Unknown
- Phases
- Phase 3
- Enrollment
- 100 participants, estimated
- Lead sponsor
- University of Zurich
- Conditions
- Right Heart Function, Chronic Obstructive Pulmonary Disease, Altitude Sickness
- Interventions
- Acetazolamide, Placebo
- First posted
- 2021-06-07
- Last updated
- 2022-11-02
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Difference in change of pulmonary artery pressure | 3 days | Difference in change of pulmonary artery pressure (RV/RA) evaluated by echocardiography at 3100 m in the acetazolamide compared to the placebo group |
| Secondary | Difference in change of pulmonary artery pressure (RV/RA) low altitude versus high altitude | 3 days | Difference in change of pulmonary artery pressure evaluated by echocardiography from 760 m baseline measurement to measurement at 3100 m in the acetazolamide compared to the placebo group |
| Secondary | Difference in cardiac output | 3 days | Difference in change of cardiac output evaluated by echocardiography in the acetazolamide compared to the placebo group |
| Secondary | Difference in right heart dimensions | 3 days | Difference in change of right heart dimensions evaluated by echocardiography in the acetazolamide compared to the placebo group |
| Secondary | Difference in right heart function | 3 days | Difference in change of tricuspid annular plane systolic sxcursion (TAPSE) evaluated by echocardiography in the acetazolamide compared to the placebo group |
| Secondary | Difference in right heart function | 3 days | Difference in change of fraction area change (FAC) evaluated by echocardiography in the acetazolamide compared to the placebo group |
| Secondary | Difference in right heart function | 3 days | Difference in change of tissue dopple S (TDI S) evaluated by echocardiography in the acetazolamide compared to the placebo group |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04915365
GET https://conductscience.org/api/trials/v1/NCT04915365/registered