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Trial · NCT04924413

L-TIL Plus Tislelizumab as First-line Treatment in Advanced Malignant Melanoma

NCT04924413, Phase 2, Terminated, Quanli Gao

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. L-TIL Plus Tislelizumab as First-line Treatment in Advanced Malignant Melanoma. Trials, record NCT04924413. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04924413

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
L-TIL Plus Tislelizumab as First-line Treatment in Advanced Malignant Melanoma
NCT number
NCT04924413
Status
Terminated
Phases
Phase 2
Enrollment
9 participants, actual
Lead sponsor
Quanli Gao
Conditions
Malignant Melanoma
Interventions
Tislelizumab
First posted
2021-06-14
Last updated
2024-07-03

Source ClinicalTrials.gov

Registered outcomes9

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryEfficacy (ORR)8 weeksThe objective response rate (ORR) at 8 weeks from baseline.
PrimaryEfficacy (ORR)16 weeksThe objective response rate (ORR) at 16 weeks.
PrimaryEfficacy (DOR)1 yearThe duration of response (DOR) at 1-year.
PrimaryEfficacy (DOR)2 yearsThe duration of response (DOR) at 2-year.
SecondaryProgression free survival (PFS)1 yearThe PFS rate at 1 year.
SecondaryProgression free survival (PFS)2 yearsThe PFS rate at 2-year.
SecondaryOverall survival (OS)1 yearThe OS rate at 1 year.
SecondaryOverall survival (OS)2 yearsThe OS rate at 2-year.
SecondarySafety (adverse events)2 yearsThe adverse events followed by treatment.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMIDListed as
33408117BACKGROUND

Source PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04924413

GET https://conductscience.org/api/trials/v1/NCT04924413/registered