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Trial · NCT04967430

TOGETHER - Toronto: Trial to Evaluate the Effect of Peginterferon Lambda for the Treatment of COVID-19

NCT04967430, Phase 3, Unknown, University Health Network, Toronto

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. TOGETHER - Toronto: Trial to Evaluate the Effect of Peginterferon Lambda for the Treatment of COVID-19. Trials, record NCT04967430. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04967430

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
TOGETHER - Toronto: Trial to Evaluate the Effect of Peginterferon Lambda for the Treatment of COVID-19
NCT number
NCT04967430
Status
Unknown
Phases
Phase 3
Enrollment
763 participants, estimated
Lead sponsor
University Health Network, Toronto
Conditions
Sars-CoV2, Covid19
Interventions
Peginterferon Lambda-1A, Placebo
First posted
2021-07-19
Last updated
2022-04-05

Source ClinicalTrials.gov

Registered outcomes30

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryCOVID-19 related urgent care visit, emergency room assessment, hospitalization or death by Day 28 (Primary efficacy endpoint)At day 28Proportion with COVID-19-related emergency room assessment, hospitalization, or death by Day 28
PrimarySARS-CoV-2 RNA negativity (Primary virological endpoint)Day 0 to Day 28The time to SARS-CoV-2 RNA negativity.
PrimaryTreatment-emergent and treatment-related serious adverse events (Primary safety endpoint)Day 0 to Day 28The rate of treatment-emergent and treatment-related serious adverse events (SAEs) by Day 28.
SecondaryRespiratory symptom resolution (Clinical Outcome #1)Day 0 to Day 28Time to resolution of respiratory symptoms.
SecondaryHospitalization (Clinical outcome #2)Day 0 to Day 28Hospitalization for any cause
SecondaryDeath (Clinical outcome #3)Day 0 to Day 28Death due to respiratory or cardiovascular causes
SecondaryAll symptom resolution (Clinical outcome #4)Day 0 to Day 28Time to resolution of all symptoms (return to usual state of heath).
SecondaryOxygen saturation on room air (Clinical outcome #5)Day 0 to Day 14Proportion of days with oxygen saturation below 93% on room air by Day 14
SecondarySeeking care from healthcare professional for COVID-19 (Clinical outcome #6)Day 0 - Day 14Proportion seeking care from primary care provider/walk-in clinic or study healthcare provider for COVID-19.
SecondaryHospital Admission (Clinical outcome #7)Day 0 to Day 28Duration of hospital admission up to Day 28

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT04967430

GET https://conductscience.org/api/trials/v1/NCT04967430/registered?page=2