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Trial · NCT04977336

Results by group71

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Time-Weighted Sum of Pain Intensity Difference (SPID) as Recorded on a Numeric Pain Rating Scale (NPRS) 0 to 48 Hours (SPID48) After the First Dose of Study DrugPlacebo100.98Standard Error 11.60units on a scale
Time-Weighted Sum of Pain Intensity Difference (SPID) as Recorded on a Numeric Pain Rating Scale (NPRS) 0 to 48 Hours (SPID48) After the First Dose of Study DrugHB/APAP115.64Standard Error 11.49units on a scale
Time-Weighted Sum of Pain Intensity Difference (SPID) as Recorded on a Numeric Pain Rating Scale (NPRS) 0 to 48 Hours (SPID48) After the First Dose of Study DrugVX-548: Low Dose112.92Standard Error 15.52units on a scale
Time-Weighted Sum of Pain Intensity Difference (SPID) as Recorded on a Numeric Pain Rating Scale (NPRS) 0 to 48 Hours (SPID48) After the First Dose of Study DrugVX-548: Mid Dose86.87Standard Error 11.33units on a scale
Time-Weighted Sum of Pain Intensity Difference (SPID) as Recorded on a Numeric Pain Rating Scale (NPRS) 0 to 48 Hours (SPID48) After the First Dose of Study DrugVX-548: High Dose137.77Standard Error 11.50units on a scale
Time-Weighted SPID as Recorded on a NPRS 0 to 24 Hours (SPID24) After the First Dose of Study DrugPlacebo31.54Standard Error 5.57units on a scale
Time-Weighted SPID as Recorded on a NPRS 0 to 24 Hours (SPID24) After the First Dose of Study DrugHB/APAP40.95Standard Error 5.52units on a scale
Time-Weighted SPID as Recorded on a NPRS 0 to 24 Hours (SPID24) After the First Dose of Study DrugVX-548: Low Dose34.36Standard Error 7.45units on a scale
Time-Weighted SPID as Recorded on a NPRS 0 to 24 Hours (SPID24) After the First Dose of Study DrugVX-548: Mid Dose24.78Standard Error 5.44units on a scale
Time-Weighted SPID as Recorded on a NPRS 0 to 24 Hours (SPID24) After the First Dose of Study DrugVX-548: High Dose45.22Standard Error 5.52units on a scale
Percentage of Participants With at Least 30 Percent (%) Reduction in NPRS at 48 Hours After the First Dose of Study DrugPlacebo67.8percentage of participants
Percentage of Participants With at Least 30 Percent (%) Reduction in NPRS at 48 Hours After the First Dose of Study DrugHB/APAP68.3percentage of participants
Percentage of Participants With at Least 30 Percent (%) Reduction in NPRS at 48 Hours After the First Dose of Study DrugVX-548: Low Dose75.8percentage of participants
Percentage of Participants With at Least 30 Percent (%) Reduction in NPRS at 48 Hours After the First Dose of Study DrugVX-548: Mid Dose62.9percentage of participants
Percentage of Participants With at Least 30 Percent (%) Reduction in NPRS at 48 Hours After the First Dose of Study DrugVX-548: High Dose83.3percentage of participants
Percentage of Participants With at Least 50% Reduction in NPRS at 48 Hours After the First Dose of Study DrugPlacebo61.0percentage of participants
Percentage of Participants With at Least 50% Reduction in NPRS at 48 Hours After the First Dose of Study DrugHB/APAP61.7percentage of participants
Percentage of Participants With at Least 50% Reduction in NPRS at 48 Hours After the First Dose of Study DrugVX-548: Low Dose72.7percentage of participants
Percentage of Participants With at Least 50% Reduction in NPRS at 48 Hours After the First Dose of Study DrugVX-548: Mid Dose56.5percentage of participants
Percentage of Participants With at Least 50% Reduction in NPRS at 48 Hours After the First Dose of Study DrugVX-548: High Dose66.7percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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