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Trial · NCT04991753

Results by group24

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change From Baseline in Disease Activity Index Score 28 Using C-reactive Protein (DAS28-CRP) at Week 12Group 1: Placebo-0.5895% Confidence Interval -1.24 to 0.07Score on a scale
Change From Baseline in Disease Activity Index Score 28 Using C-reactive Protein (DAS28-CRP) at Week 12Group 2: Nipocalimab-1.0395% Confidence Interval -1.66 to -0.40Score on a scale
Percentage of Participants Who Achieved American College of Rheumatology (ACR) 20 at Week 12Group 1: Placebo20.0-1.24 to 0.07Percentage of Participants
Percentage of Participants Who Achieved American College of Rheumatology (ACR) 20 at Week 12Group 2: Nipocalimab45.5-1.66 to -0.40Percentage of Participants
Percentage of Participants Who Achieved American College of Rheumatology (ACR) 50 at Week 12Group 1: Placebo5.0-1.24 to 0.07Percentage of Participants
Percentage of Participants Who Achieved American College of Rheumatology (ACR) 50 at Week 12Group 2: Nipocalimab15.2-1.66 to -0.40Percentage of Participants
Percentage of Participants Who Achieved American College of Rheumatology (ACR) 70 at Week 12Group 1: Placebo0-1.24 to 0.07Percentage of Participants
Percentage of Participants Who Achieved American College of Rheumatology (ACR) 70 at Week 12Group 2: Nipocalimab12.1-1.66 to -0.40Percentage of Participants
Percentage of Participants Who Achieved American College of Rheumatology (ACR) 90 at Week 12Group 1: Placebo0-1.24 to 0.07Percentage of Participants
Percentage of Participants Who Achieved American College of Rheumatology (ACR) 90 at Week 12Group 2: Nipocalimab6.1-1.66 to -0.40Percentage of Participants
Percentage of Participants Who Achieved Disease Activity Index Score 28 Using C-reactive Protein (DAS28-CRP) Remission at Week 12Group 1: Placebo10.0-1.24 to 0.07Percentage of Participants
Percentage of Participants Who Achieved Disease Activity Index Score 28 Using C-reactive Protein (DAS28-CRP) Remission at Week 12Group 2: Nipocalimab21.2-1.66 to -0.40Percentage of Participants
Percentage of Participants Who Achieved Disease Activity Index Score 28 Using C-reactive Protein (DAS28-CRP) Low Disease Activity (LDA) European League Against Rheumatism (EULAR) at Week 12Group 1: Placebo10.0-1.24 to 0.07Percentage of Participants
Percentage of Participants Who Achieved Disease Activity Index Score 28 Using C-reactive Protein (DAS28-CRP) Low Disease Activity (LDA) European League Against Rheumatism (EULAR) at Week 12Group 2: Nipocalimab21.2-1.66 to -0.40Percentage of Participants
Change From Baseline in Health Assessment Questionnaire - Disability Index (HAQ-DI) Score at Week 12Group 1: Placebo-0.2195% Confidence Interval -0.45 to 0.04Score on a scale
Change From Baseline in Health Assessment Questionnaire - Disability Index (HAQ-DI) Score at Week 12Group 2: Nipocalimab-0.4295% Confidence Interval -0.66 to -0.19Score on a scale
Percentage of Participants With Treatment-emergent Adverse Events (TEAEs)Group 1: Placebo60.0-1.24 to 0.07Percentage of Participants
Percentage of Participants With Treatment-emergent Adverse Events (TEAEs)Group 2: Nipocalimab81.8-1.66 to -0.40Percentage of Participants
Percentage of Participants With Treatment-emergent Serious Adverse Events (TESAEs)Group 1: Placebo0-1.24 to 0.07Percentage of Participants
Percentage of Participants With Treatment-emergent Serious Adverse Events (TESAEs)Group 2: Nipocalimab9.1-1.66 to -0.40Percentage of Participants

Source ClinicalTrials.govtrials-2026-11-12-0.4.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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