Registered outcomes16

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

1 to 16 of 16

List	Outcome	Time frame	Description
Primary	Laryngeal Preservation rate at 3-month post-radiotherapy	3-month post-radiotherapy	defined as the absence of any residual disease that would justify salvage total laryngectomy
Secondary	Overall response rate of induction therapy	2 weeks after the 3th cycle of induction therapy	Overall response rate of induction therapy evaluated by head and neck MR/CT, laryngoscopy using Recist 1.1 Criteria
Secondary	Overall response rate of treatment	3 months post-radiotherapy	Overall response rate of treatment evaluated by head and neck MR/CT, laryngoscopy using Recist 1.1 Criteria
Secondary	Pathological complete response rate of the patients receiving surgical resection	Within 3 weeks after surgery	Pathological complete response rate of the patients receiving surgical resection, evaluated by experienced pathologists
Secondary	Major pathologic response rate of the patients receiving surgical resection	Within 3 weeks after surgery	Major pathologic response rate, defined as no more than 10% of residual viable tumor, evaluated by experienced pathologists.
Secondary	Overall survival rate at 1 year	One year post-radiotherapy	Overall survival rate at 1 year
Secondary	Overall survival rate at 2 year	Two year post-radiotherapy	Overall survival rate at 2 year
Secondary	Progression-free survival rate at 1 year	One year post-radiotherapy	Progression-free survival rate at 1 year
Secondary	Progression-free survival rate at 2 year	Two year post-radiotherapy	Progression-free survival rate at 2 year
Secondary	Laryngeal Preservation rate at 1 year	One year post-radiotherapy	Laryngeal Preservation rate at 1 year
Secondary	Laryngeal Preservation rate at 2 year	Two year post-radiotherapy	Laryngeal Preservation rate at 2 year
Secondary	Adverse Effect	One year post-radiotherapy	Adverse Effect, evaluated by CTCAE 4.0.03
Other	Laryngeal Preservation rate at 3 month post-radiotherapy by different biomarker subgroups	3-month post-radiotherapy	Experimental Biomarker Analysis: the relationship with different biomarkers and 3 month laryngeal preservation rate
Other	Overall response rate of induction therapy, by different biomarker subgroups	2 weeks after the 3th cycle of induction therapy	Experimental Biomarker Analysis: the relationship with different biomarkers and overall response rate of induction therapy
Other	Pathological complete response rate by different biomarker subgroups	Within 3 weeks after surgery	Experimental Biomarker Analysis: the relationship with different biomarkers and pathological complete response rate of the patients receiving surgical resection
Other	Major pathologic response rate by different biomarker subgroups	Within 3 weeks after surgery	Experimental Biomarker Analysis: the relationship with different biomarkers and major pathologic response rate of the patients receiving surgical resection

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT04995120/registered

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