Trial · NCT04996030
A Study for Oral SY-2101 for Participants With Acute Promyelocytic Leukemia
NCT04996030, Phase 1, Suspended, Syros Pharmaceuticals
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. A Study for Oral SY-2101 for Participants With Acute Promyelocytic Leukemia. Trials, record NCT04996030. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT04996030
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study for Oral SY-2101 for Participants With Acute Promyelocytic Leukemia
- NCT number
- NCT04996030
- Status
- Suspended
- Phases
- Phase 1
- Enrollment
- 16 participants, actual
- Lead sponsor
- Syros Pharmaceuticals
- Conditions
- Acute Promyelocytic Leukemia
- Interventions
- SY-2101, Arsenic Trioxide
- First posted
- 2021-08-09
- Last updated
- 2024-01-23
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Single-Dose Module: Maximum Observed Plasma Concentration (Cmax) of SY-2101 | Predose and up to 168 hours postdose | |
| Primary | Single-Dose Module: Area Under the Curve (AUC) of SY-2101 | Predose and up to 168 hours postdose | |
| Primary | Multiple-Dose Module: Cmax of SY-2101 | Predose and up to 6 hours postdose on Day 5 and up to 4 hours postdose on Day 26 | |
| Primary | Multiple-Dose Module: AUC of SY-2101 | Predose and up to 6 hours postdose on Day 5 and up to 4 hours postdose on Day 26 | |
| Secondary | Single-Dose Module: Cmax of ATO | Predose and up to 168 hours postdose | |
| Secondary | Single-Dose Module: AUC of ATO | Predose and up to 168 hours postdose | |
| Secondary | Multiple-Dose Module: Cmax of ATO | Predose and up to 6 hours postdose on Day 5 and up to 4 hours postdose on Day 26 | |
| Secondary | Multiple-Dose Module: AUC of ATO | Predose and up to 6 hours postdose on Day 5 and up to 4 hours postdose on Day 26 | |
| Secondary | Number of Participants With Adverse Events | up to Day 23 for single-dose module and up to Day 56 for multiple-dose module |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 40020161 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT04996030
GET https://conductscience.org/api/trials/v1/NCT04996030/registered