Trial · NCT05008939
Sevoflurane for Treatment-Resistant Depression
NCT05008939, Not applicable, Unknown, Shanghai First Maternity and Infant Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Sevoflurane for Treatment-Resistant Depression. Trials, record NCT05008939. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05008939
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Sevoflurane for Treatment-Resistant Depression
- NCT number
- NCT05008939
- Status
- Unknown
- Phases
- Not applicable
- Enrollment
- 15 participants, estimated
- Lead sponsor
- Shanghai First Maternity and Infant Hospital
- Conditions
- Depressive Disorder, Treatment-Resistant, Depressive Disorder, Major
- Interventions
- Sevoflurane, Placebo
- First posted
- 2021-08-17
- Last updated
- 2021-08-17
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Rates of treatment responses in 17-item Hamilton Depression Rating Scale (HDRS-17) | 24 hours after the end of treatment | ≥50% HDRS-17 reduction in depressive symptoms |
| Secondary | Rates of treatment responses in HDRS-17 | 2 hours, 7 days,14 days and 28 days after the end of treatment | ≥50% HDRS-17 reduction in depressive symptoms |
| Secondary | Rates of remissions in HDRS-17 | 2 hours, 24 hours, 7 days,14 days and 28 days after the end of treatment | HDRS-17 ≤7 points |
| Secondary | Rates of treatment responses in Montgomery-Åsberg Depression Rating Scale (MADRS) | 2 hours, 24 hours, 7 days,14 days and 28 days after the end of treatment | ≥50% MADRS reduction in the baseline score |
| Secondary | Rates of remissions in MADRS | 2 hours, 24 hours, 7 days,14 days and 28 days after the end of treatment | MADRS \<10 |
| Secondary | The assessment of depression with self-rating scale | 2 hours, 24 hours, 7 days,14 days and 28 days after the end of treatment | The changes of score in Patient Health Questionnaire-9 (PHQ-9) |
| Secondary | The assessment of anxiety by psychiatrist | 2 hours, 24 hours, 7 days,14 days and 28 days after the end of treatment | The changes of score in Hamilton Anxiety Rating Scale (HAMA) |
| Secondary | The assessment of anxiety with self-rating scale | 2 hours, 24 hours, 7 days,14 days and 28 days after the end of treatment | The changes of score in Generalized Anxiety Disorder Screener (GAD-7) |
| Secondary | The assessment of improvement by psychiatrist | 2 hours, 24 hours, 7 days,14 days and 28 days after the end of treatment | The changes of score in Clinical Global Impression (CGI) |
| Secondary | The assessment of improvement with self-rating scale | 2 hours, 24 hours, 7 days,14 days and 28 days after the end of treatment | The changes of score in Patient Global Impressions of Improvement (PGI-I) |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers11
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05008939
GET https://conductscience.org/api/trials/v1/NCT05008939/registered