Trial · NCT05018286
Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.
NCT05018286, Phase 3, Active not recruiting, VectivBio AG
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome. Trials, record NCT05018286. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05018286
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.
- NCT number
- NCT05018286
- Status
- Active not recruiting
- Phases
- Phase 3
- Enrollment
- 158 participants, actual
- Lead sponsor
- VectivBio AG
- Conditions
- Short Bowel Syndrome
- Interventions
- Apraglutide
- First posted
- 2021-08-24
- Last updated
- 2025-07-02
Source ClinicalTrials.gov
Registered outcomes21
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Adverse events (AE) | From baseline to week 208 | System organ class, frequency and severity |
| Primary | Clinical chemistry | From baseline to week 208 | Clinical Chemistry panel of analytes will be examined for clinically significant changes. |
| Primary | Hematology | From baseline to week 208 | Hematology panel of analytes will be examined for clinically significant changes. |
| Primary | Hemostasis | From baseline to week 104 | Hemostasis INR will be examined for clinically significant changes. |
| Primary | Urinalysis | From baseline to week 208 | Urinanalysis panel of analytes will be examined for clinically significant changes. |
| Primary | Occurrence of clinically relevant changes in vital signs | From baseline to week 208 | * Systolic and diastolic blood pressure in mmHg will be examined for clinically significant changes. * Heart rate in Beats per Minute (BPM) will be examined for clinically significant changes. |
| Primary | Occurrence of clinically relevant changes in electrocardiogram | From baseline to week 208 | ECG; intervals and rhythm |
| Secondary | Change from baseline in PS volume | From baseline to week 208 | |
| Secondary | Change from baseline in PS frequency | From baseline to week 208 | Change in PS days/week from baseline to week 104 |
| Secondary | Clinically significant changes in PS total energy | From baseline to week 208 | Units: kcal |
1 to 10 of 21Source ClinicalTrials.gov
See all 21 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05018286
GET https://conductscience.org/api/trials/v1/NCT05018286/registered?page=2