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Trial · NCT05019521

Results by group805

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Rate of Change From Baseline to Week 52 in the Square Root (Sqrt) of Total Geographic Atrophy (GA) Lesion Area in the Study Eye as Measured by Fundus Autofluorescence (FAF)Danicopan 100 mg BID0.465Standard Error 0.0289mm/year
Rate of Change From Baseline to Week 52 in the Square Root (Sqrt) of Total Geographic Atrophy (GA) Lesion Area in the Study Eye as Measured by Fundus Autofluorescence (FAF)Danicopan 200 mg BID0.391Standard Error 0.0306mm/year
Rate of Change From Baseline to Week 52 in the Square Root (Sqrt) of Total Geographic Atrophy (GA) Lesion Area in the Study Eye as Measured by Fundus Autofluorescence (FAF)Danicopan 400 mg QD0.443Standard Error 0.0301mm/year
Rate of Change From Baseline to Week 52 in the Square Root (Sqrt) of Total Geographic Atrophy (GA) Lesion Area in the Study Eye as Measured by Fundus Autofluorescence (FAF)Placebo0.406Standard Error 0.0304mm/year
Change From Baseline to Week 104 in the Sqrt of the Total GA Lesion Area in the Study Eye as Measured by FAFDanicopan 100 mg BID0.892Standard Deviation 0.4545mm
Change From Baseline to Week 104 in the Sqrt of the Total GA Lesion Area in the Study Eye as Measured by FAFDanicopan 200 mg BID0.705Standard Deviation 0.3831mm
Change From Baseline to Week 104 in the Sqrt of the Total GA Lesion Area in the Study Eye as Measured by FAFDanicopan 400 mg QD0.859Standard Deviation 0.3468mm
Change From Baseline to Week 104 in the Sqrt of the Total GA Lesion Area in the Study Eye as Measured by FAFPlacebo - Danicopan 100 mg BID0.668Standard Deviation 0.4866mm
Change From Baseline to Week 104 in the Sqrt of the Total GA Lesion Area in the Study Eye as Measured by FAFPlacebo - Danicopan 200 mg BID0.585Standard Deviation 0.1396mm
Change From Baseline to Week 104 in the Sqrt of the Total GA Lesion Area in the Study Eye as Measured by FAFPlacebo - Danicopan 400 mg QD0.787Standard Deviation 0.1858mm
Change From Baseline to Week 52 and Week 104 in the Total GA Lesion Area in the Study Eye as Measured by FAFDanicopan 100 mg BIDChange at Week 522.347Standard Deviation 1.2972mm^2
Change From Baseline to Week 52 and Week 104 in the Total GA Lesion Area in the Study Eye as Measured by FAFDanicopan 200 mg BIDChange at Week 522.044Standard Deviation 1.2280mm^2
Change From Baseline to Week 52 and Week 104 in the Total GA Lesion Area in the Study Eye as Measured by FAFDanicopan 400 mg QDChange at Week 522.274Standard Deviation 1.4482mm^2
Change From Baseline to Week 52 and Week 104 in the Total GA Lesion Area in the Study Eye as Measured by FAFPlaceboChange at Week 522.057Standard Deviation 1.2016mm^2
Change From Baseline to Week 52 and Week 104 in the Total GA Lesion Area in the Study Eye as Measured by FAFPlacebo - Danicopan 100 mg BIDChange at Week 521.887Standard Deviation 1.1212mm^2
Change From Baseline to Week 52 and Week 104 in the Total GA Lesion Area in the Study Eye as Measured by FAFPlacebo - Danicopan 200 mg BIDChange at Week 521.716Standard Deviation 0.9095mm^2
Change From Baseline to Week 52 and Week 104 in the Total GA Lesion Area in the Study Eye as Measured by FAFPlacebo - Danicopan 400 mg QDChange at Week 522.553Standard Deviation 1.3938mm^2
Change From Baseline to Week 52 and Week 104 in the Total GA Lesion Area in the Study Eye as Measured by FAFDanicopan 100 mg BIDChange at Week 1044.311Standard Deviation 2.8803mm^2
Change From Baseline to Week 52 and Week 104 in the Total GA Lesion Area in the Study Eye as Measured by FAFDanicopan 200 mg BIDChange at Week 1043.223Standard Deviation 2.3784mm^2
Change From Baseline to Week 52 and Week 104 in the Total GA Lesion Area in the Study Eye as Measured by FAFDanicopan 400 mg QDChange at Week 1044.504Standard Deviation 2.1300mm^2

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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