Trial · NCT05020457
SI-B001 Combined With Chemotherapy in the Treatment of EGFR/ALK WT Recurrent or Metastatic NSCLC.
NCT05020457, Phase 2, Active not recruiting, Sichuan Baili Pharmaceutical Co., Ltd.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. SI-B001 Combined With Chemotherapy in the Treatment of EGFR/ALK WT Recurrent or Metastatic NSCLC. Trials, record NCT05020457. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05020457
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- SI-B001 Combined With Chemotherapy in the Treatment of EGFR/ALK WT Recurrent or Metastatic NSCLC.
- NCT number
- NCT05020457
- Status
- Active not recruiting
- Phases
- Phase 2
- Enrollment
- 69 participants, actual
- Lead sponsor
- Sichuan Baili Pharmaceutical Co., Ltd.
- Conditions
- Non Small Cell Lung Cancer
- Interventions
- SI-B001, AP or TP, Docetaxel
- First posted
- 2021-08-25
- Last updated
- 2025-09-26
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | ORR | Up to approximately 24 months | Objective Response Rate |
| Primary | Optimal combination dose (only IIa) | Up to approximately 24 months | Optimal combination dose of SI-B001 with chemotherapy (only IIa) |
| Secondary | OS | Up to approximately 24 months | Overall Survival |
| Secondary | PFS | Up to approximately 24 months | Progression Free Survival |
| Secondary | DCR | Up to approximately 24 months | Disease Control Rate |
| Secondary | DOR | Up to approximately 24 months | Duration of Response |
| Secondary | TEAE | Up to approximately 24 months | Treatment Emergent Adverse Events |
| Secondary | Cmax | Up to approximately 24 months | Maximum serum concentration |
| Secondary | Tmax | Up to approximately 24 months | Time to maximum serum concentration |
| Secondary | Ctrough | Up to approximately 24 months | Minimum serum concentration |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05020457
GET https://conductscience.org/api/trials/v1/NCT05020457/registered