Sex Difference Effects on Postoperative Sleep, Inflammation and Cognition in Patients Undergoing General Anesthesia
NCT05059548, Unknown, Shengjing Hospital
Trial 9
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Sex Difference Effects on Postoperative Sleep, Inflammation and Cognition in Patients Undergoing General Anesthesia | ClinicalTrials.gov |
| NCT number | NCT05059548 | ClinicalTrials.gov |
| Status | Unknown | ClinicalTrials.gov |
| Enrollment | 100 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Shengjing Hospital | ClinicalTrials.gov |
| Conditions | Sex Differences, Postoperative Sleep Quality, Postoperative Pain, Inflammation Function, Postoperative Cognitive Function | ClinicalTrials.gov |
| Interventions | Video-Assisted Thoracoscopic Surgery | ClinicalTrials.gov |
| First posted | 2021-09-28 | ClinicalTrials.gov |
| Last updated | 2021-09-28 | ClinicalTrials.gov |
Registered outcomes 14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | sleep quality of one night before surgery | one night before surgery | use the athens insomnia scale to evaluate subjective sleep quality (0 to 24 points, with ≥ 6 points indicating a diagnosis of insomnia) | ClinicalTrials.gov |
| Primary | sleep quality of first night after surgery | first night after surgery | use the athens insomnia scale to evaluate subjective sleep quality (0 to 24 points, with ≥ 6 points indicating a diagnosis of insomnia) | ClinicalTrials.gov |
| Primary | sleep quality of third night after surgery | third night after surgery | use the athens insomnia scale to evaluate subjective sleep quality (0 to 24 points, with ≥ 6 points indicating a diagnosis of insomnia) | ClinicalTrials.gov |
| Primary | preoperative inflammation function | three days before surgery | evaluate systemic immune inflammation index (SII) before operation | ClinicalTrials.gov |
| Primary | preoperative inflammation function | three days before surgery | evaluate neutrophil / lymphocyte ratio (NLR)before operation | ClinicalTrials.gov |
| Primary | preoperative inflammation function | three days before surgery | evaluate platelet / lymphocyte ratio (PLR) before operation | ClinicalTrials.gov |
| Primary | preoperative inflammation function | three days before surgery | evaluate monocyte / lymphocyte ratio (MLR) before operation | ClinicalTrials.gov |
| Primary | postoperative inflammation function | three days after surgery | evaluate systemic immune inflammation index (SII) after operation | ClinicalTrials.gov |
| Primary | postoperative inflammation function | three days after surgery | evaluate neutrophil / lymphocyte ratio (NLR) after operation | ClinicalTrials.gov |
| Primary | postoperative inflammation function | three days after surgery | evaluate platelet / lymphocyte ratio (PLR) after operation | ClinicalTrials.gov |
| Primary | postoperative inflammation function | three days after surgery | evaluate monocyte / lymphocyte ratio (MLR) after operation | ClinicalTrials.gov |
| Primary | neuropsychological test | Neuropsychological tests were carried out the day before and 5 to 7 days after surgery. The second neuropsychological test time for control subjects was 6 to 9 d | The neuropsychological test battery included the tests used to evaluate patients for delayed neurocognitive recovery in the International Study of Post-Operative Cognitive Dysfunction: (1) word learning: visual verbal learning test based on the Rey's auditory recall of words; (2) word recall: the number or words recalled from visual verbal learning trials after a 20-min delay; (3) cognitive flexibility: including trail making test A and B; (4) distractibility: Stroop color word interference test; and (5) working memory: letter-digit coding. If a patient exhibited delirium at a testing time, neuropsychological evaluation was postponed 3 days. | ClinicalTrials.gov |
| Secondary | visual analog scale(VAS) score after surgery | 24 hours after surgery | evaluate VAS (0-10 points)score 24 hours after surgery | ClinicalTrials.gov |
| Secondary | postoperative adverse effects | 24 hours after surgery | evaluate postoperative adverse effect 24 hours after surgery | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 4
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Trail Making Test A | Primary outcome | ConductCognition |
| Trail Making Test B | Primary outcome | ConductCognition |
| Verbal Learning | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)