Trial · NCT05084521
Interest of Famotidine in Children With Sickle Cell Disease
NCT05084521, Phase 2, Phase 3, Completed, Assistance Publique - Hôpitaux de Paris
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Interest of Famotidine in Children With Sickle Cell Disease. Trials, record NCT05084521. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05084521
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Interest of Famotidine in Children With Sickle Cell Disease
- NCT number
- NCT05084521
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 30 participants, actual
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Conditions
- Sickle Cell Disease
- Interventions
- Famotidine 400 mg/50 mL
- First posted
- 2021-10-19
- Last updated
- 2025-10-08
- Other registries' IDs
- eudract:2021-001351-13
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Difference in plasma concentration of soluble P-selectin | 29 days | Measurement by ELISA technique before and after 29 days of treatment |
| Secondary | Difference in plasma concentration of soluble adhesion molecule: E-selectin | 29 days | Measurement by ELISA technique before and after 29 days of treatment |
| Secondary | Difference in plasma concentration of soluble adhesion molecule: VCAM-1 | 29 days | Measurement by ELISA technique before and after 29 days of treatment |
| Secondary | Difference in plasma concentration of soluble adhesion molecule: ICAM-1 | 29 days | Measurement by ELISA technique before and after 29 days of treatment |
| Secondary | Differences in blood values: hemoglobin, reticulocytes, AST, free bilirubin, LDH, and CRP | 29 days | Dosage on D0 and D29 |
| Secondary | Occurrence of serious or non-serious adverse event(s) | 36 days | |
| Secondary | Occurrence of vaso-occlusive crisis | 36 days |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 37722599 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05084521
GET https://conductscience.org/api/trials/v1/NCT05084521/registered