Trial · NCT05087381
Randomized-controlled Trial of the Effectiveness of COVID-19 Early Treatment in Community
NCT05087381, Phase 4, Completed, Chulalongkorn University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Randomized-controlled Trial of the Effectiveness of COVID-19 Early Treatment in Community. Trials, record NCT05087381. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05087381
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Randomized-controlled Trial of the Effectiveness of COVID-19 Early Treatment in Community
- NCT number
- NCT05087381
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 1,200 participants, actual
- Lead sponsor
- Chulalongkorn University
- Conditions
- Treatment Efficacy
- Interventions
- FluvoxaMINE Maleate 50 MG, Fluvoxamine, Bromhexine, Fluvoxamine, Cyproheptadine, Niclosamide Pill, Niclosamide, Bromhexine
- First posted
- 2021-10-21
- Last updated
- 2022-11-04
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Hospital admission or mortality related to COVID-19 | Within 28 days | Contacts with health services reported by patients and/or captured by reports of patients' medical records |
| Primary | Time taken to self- report recovery | Enrolment through final day of participation | Patient reports the day they feel recovered |
| Primary | Progression to severe COVID-19 Disease | Enrolment through final day of participation | O2 saturation \<92% on room air (in two consecutive measurements at least 2 hours apart) OR 2) requirement of hospitalization OR 3) need for artificial ventilation OR 4) death. |
| Secondary | Reduction (change) in GI viral shedding (by PCR) | Days 0,7,14 | Fecal swabs |
| Secondary | Change in respiratory viral clearance (by PCR) | Days 0,7,14 | Oropharyngeal swabs |
| Secondary | Time to resolution of a fever | Enrolment through final day of participation | Online diary |
| Secondary | Negative effects on well being | Days 0,7,15,28,60 | WHO 5 Well Being Index via online diary or telephone |
| Other | Incidence of Adverse Events (AEs) | Enrolment through 30 days after final day of participation | Composite counts by Adverse Events and Serious Adverse Events |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 38516100 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05087381
GET https://conductscience.org/api/trials/v1/NCT05087381/registered