Trial · NCT05093621
Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure
NCT05093621, Phase 3, Completed, Yale University; results first posted 2024-10-15
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure. Trials, record NCT05093621. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05093621
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Torsemide Comparison With Furosemide for Management of Patients With Stable Heart Failure
- NCT number
- NCT05093621
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 47 participants, actual
- Lead sponsor
- Yale University
- Conditions
- Heart Failure
- Interventions
- Furosemide, Torsemide
- First posted
- 2021-10-26
- Last updated
- 2024-10-15
- Results first posted
- 2024-10-15
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Participants All-cause Mortality, Measured at 1 Year. | 30 days and one year | All-cause mortality as measured by phone calls at 30 days and 1 year |
| Secondary | All-cause Hospitalization | up to one year | At least one hospitalization for any reason up to one year |
| Secondary | Total Hospitalizations | up to one year | Total number of hospitalizations total number of hospitalizations in one year |
| Secondary | Change in Weight | up to one year | Change in weight up to one year |
Source ClinicalTrials.gov
Outcomes4
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of Participants All-cause Mortality, Measured at 1 Year. | 30 days and one year | Data presented here is from Yale site only. Only data from the Yale site was collected and analyzed. Data from other site could not be collected. | Participants | COUNT_OF_PARTICIPANTS |
| SECONDARY | All-cause Hospitalization | up to one year | Data presented here is from Yale site only. Only data from the Yale site was collected and analyzed. Data from other site could not be collected. | Participants | COUNT_OF_PARTICIPANTS |
| SECONDARY | Total Hospitalizations | up to one year | Data presented here is from Yale site only. Only data from the Yale site was collected and analyzed. Data from other site could not be collected. | hospitalizations | MEAN |
| SECONDARY | Change in Weight | up to one year | Data presented here is from Yale site only. Only data from the Yale site was collected and analyzed. Data from other site could not be collected. | kilograms | MEAN |
Source ClinicalTrials.gov
Results by group10
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Number of Participants All-cause Mortality, Measured at 1 Year. | Furosemide | 30 days | 0 | Participants | |
| Number of Participants All-cause Mortality, Measured at 1 Year. | Torsemide | 30 days | 0 | Participants | |
| Number of Participants All-cause Mortality, Measured at 1 Year. | Furosemide | one year | 0 | Participants | |
| Number of Participants All-cause Mortality, Measured at 1 Year. | Torsemide | one year | 1 | Participants | |
| All-cause Hospitalization | Furosemide | 6 | Participants | ||
| All-cause Hospitalization | Torsemide | 7 | Participants | ||
| Total Hospitalizations | Furosemide | 0 | Full Range 0 to 1 | hospitalizations | |
| Total Hospitalizations | Torsemide | 0 | Full Range 0 to 4 | hospitalizations | |
| Change in Weight | Furosemide | -1.84 | Standard Deviation 4.9 | kilograms | |
| Change in Weight | Torsemide | -3.04 | Standard Deviation 10.22 | kilograms |
Source ClinicalTrials.gov
Participant flow8
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Furosemide | 23 | |
| Overall Study | STARTED | Torsemide | 24 | |
| Overall Study | Yale Site Participants | Furosemide | 18 | |
| Overall Study | Yale Site Participants | Torsemide | 18 | |
| Overall Study | COMPLETED | Furosemide | 23 | |
| Overall Study | COMPLETED | Torsemide | 24 | |
| Overall Study | NOT COMPLETED | Furosemide | 0 | |
| Overall Study | NOT COMPLETED | Torsemide | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Furosemide | 0 | 23 |
| Total, all-cause mortality | Torsemide | 1 | 24 |
| Total, other adverse events | Furosemide | 0 | 23 |
| Total, other adverse events | Torsemide | 0 | 24 |
| Total, serious adverse events | Furosemide | 0 | 23 |
| Total, serious adverse events | Torsemide | 0 | 24 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 39196651 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons3
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Furosemide vs Torsemide: All-cause Hospitalization | Trial comparisons |
| Furosemide vs Torsemide: deaths from any cause | Trial comparisons |
| Furosemide vs Torsemide: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05093621
GET https://conductscience.org/api/trials/v1/NCT05093621/registered