Trial · NCT05097014
CHF5993 and CHF1535 pMDI on Lung Hyperinflation and Exercise Endurance Time in Subjects With COPD
NCT05097014, Phase 4, Completed, Chiesi Farmaceutici S.p.A.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. CHF5993 and CHF1535 pMDI on Lung Hyperinflation and Exercise Endurance Time in Subjects With COPD. Trials, record NCT05097014. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05097014
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- CHF5993 and CHF1535 pMDI on Lung Hyperinflation and Exercise Endurance Time in Subjects With COPD
- NCT number
- NCT05097014
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 106 participants, actual
- Lead sponsor
- Chiesi Farmaceutici S.p.A.
- Conditions
- Chronic Obstructive Pulmonary Disease
- Interventions
- CHF5993, CHF1535, Matched placebo
- First posted
- 2021-10-27
- Last updated
- 2023-03-24
- Other registries' IDs
- eudract:2020-004718-36
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Inspiratory capacity (IC) prior to Constant Work Rate Cycle Ergometry (CWRCE) test | 3 weeks of treatment | Change from baseline in 2-hour post-dose |
| Secondary | IC at Isotime, defined as the shortest CWRCE test duration among baseline and end of treatment period. | 3 weeks of treatment | Change from baseline |
| Secondary | Exercise endurance time (EET) | 3 weeks of treatment | Change from baseline in 2-hour post-dose |
| Other | EET between CHF5993 and CHF1535 | 3 weeks of treatment | Change from baseline in 2-hour post-dose |
| Other | Pre-dose morning Forced Expiratory Volume in 1 second (FEV1) | 3 weeks of treatment | Change from baseline |
| Other | Pre-dose Forced Vital Capacity (FVC) | 3 weeks of treatment | Change from baseline |
| Other | Functional Residual Capacity (FRC) | 3 weeks of treatment | Change from baseline in 2-hour post-dose |
| Other | Pre-dose IC | 3 weeks of treatment | Change from baseline |
| Other | Residual Volume (RV) | 3 weeks of treatment | Change from baseline in 2-hour post-dose |
| Other | RV/Total Lung Capacitity (TLC) ratio | 3 weeks of treatment | Change from baseline in 2-hour post-dose |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 39420338 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05097014
GET https://conductscience.org/api/trials/v1/NCT05097014/registered