Trial · NCT05098067
Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy
NCT05098067, Phase 2, Completed, Women and Infants Hospital of Rhode Island; results first posted 2024-02-07
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy. Trials, record NCT05098067. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05098067
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Capsaicin Cream as an Adjunctive Therapy for Nausea and Vomiting of Pregnancy
- NCT number
- NCT05098067
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 30 participants, actual
- Lead sponsor
- Women and Infants Hospital of Rhode Island
- Conditions
- Hyperemesis Gravidarum, Nausea Gravidarum, Vomiting of Pregnancy
- Interventions
- Capsaicin Topical Cream, Metoclopramide, Ondansetron, Lactated Ringers, Intravenous
- First posted
- 2021-10-28
- Last updated
- 2024-02-07
- Results first posted
- 2024-02-07
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Time to Symptom Control | 180 minutes | Time to perceived symptom control as measured by time elapsed between metoclopramide administration and patient request for discharge. |
| Secondary | Number of Antiemetics Needed for Symptom Control | 180 minutes |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Time to Symptom Control | 180 minutes | minutes | MEDIAN | |
| SECONDARY | Number of Antiemetics Needed for Symptom Control | 180 minutes | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group12
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Time to Symptom Control | Intervention Group | 72 | Inter-Quartile Range 56 to 86 | minutes | |
| Time to Symptom Control | Placebo Group | 87 | Inter-Quartile Range 69 to 111 | minutes | |
| Number of Antiemetics Needed for Symptom Control | Intervention Group | 1 additional antiemetic | 2 | Participants | |
| Number of Antiemetics Needed for Symptom Control | Placebo Group | 1 additional antiemetic | 4 | Participants | |
| Number of Antiemetics Needed for Symptom Control | Intervention Group | 2 additional antiemetics | 1 | Participants | |
| Number of Antiemetics Needed for Symptom Control | Placebo Group | 2 additional antiemetics | 1 | Participants | |
| Number of Antiemetics Needed for Symptom Control | Intervention Group | 3 additional antiemetics | 1 | Participants | |
| Number of Antiemetics Needed for Symptom Control | Placebo Group | 3 additional antiemetics | 0 | Participants | |
| Number of Antiemetics Needed for Symptom Control | Intervention Group | 4 additional antiemetics | 0 | Participants | |
| Number of Antiemetics Needed for Symptom Control | Placebo Group | 4 additional antiemetics | 0 | Participants |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 results by groupParticipant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Intervention Group | 15 | |
| Overall Study | STARTED | Placebo Group | 15 | |
| Overall Study | COMPLETED | Intervention Group | 15 | |
| Overall Study | COMPLETED | Placebo Group | 15 | |
| Overall Study | NOT COMPLETED | Intervention Group | 0 | |
| Overall Study | NOT COMPLETED | Placebo Group | 0 |
Source ClinicalTrials.gov
Adverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Skin irritation | Skin and subcutaneous tissue disorders | Intervention Group | 10 | 15 | 10 |
| other | Skin irritation | Skin and subcutaneous tissue disorders | Placebo Group | 0 | 15 | 0 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Intervention Group | 0 | 15 |
| Total, all-cause mortality | Placebo Group | 0 | 15 |
| Total, other adverse events | Intervention Group | 10 | 15 |
| Total, other adverse events | Placebo Group | 0 | 15 |
| Total, serious adverse events | Intervention Group | 0 | 15 |
| Total, serious adverse events | Placebo Group | 0 | 15 |
Source ClinicalTrials.gov
Papers9
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Intervention Group vs Placebo Group: deaths from any cause | Trial comparisons |
| Intervention Group vs Placebo Group: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05098067
GET https://conductscience.org/api/trials/v1/NCT05098067/registered