Trial · NCT05118542
Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis
NCT05118542, Phase 3, Completed, Universitas Indonesia
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis. Trials, record NCT05118542. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05118542
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Hyperthyroidism and Its Treatment in Graves' Disease to Early Marker of Atherosclerosis
- NCT number
- NCT05118542
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 36 participants, actual
- Lead sponsor
- Universitas Indonesia
- Conditions
- Hyperthyroidism, Graves Disease, Atherosclerosis of Artery, Pathophysiology
- Interventions
- Propylthiouracil, Methimazole
- First posted
- 2021-11-12
- Last updated
- 2021-11-12
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pulse Wave Velocity | Change from Baseline to 3 month follow-up | Pulse wave velocity was measured using radio frequency ultrasound in supine position at both left and right carotid artery |
| Primary | carotid intima media thickness | Change from Baseline to 3 month follow-up | cIMT was measured using radio frequency ultrasound in supine position at both left and right carotid artery |
| Secondary | HOMA-IR | Change from Baseline to 3 month follow-up | HOMA-IR was calculated from patient fasting blood glucose and fasting insulin, which both were obtained through serum of the patient. Fasting blood glucose was measured using ECLIA methods with Abbott reagent, while fasting insulin were measured using ELISA with D\&G International Inc. kit |
| Secondary | LDL-R | Change from Baseline to 3 month follow-up | LDL-R was measured from the patient serum using ELISA with D\&G International Inc. kit |
| Secondary | NFkB | Change from Baseline to 3 month follow-up | NFkB was measured from the patient serum using ELISA with Cusabio kit |
| Secondary | sICAM-1 | Change from Baseline to 3 month follow-up | sICAM-1 was measured from the patient serum using ELISA with D\&G International Inc. kit |
| Secondary | sVCAM-1 | Change from Baseline to 3 month follow-up | sVCAM-1 was measured from the patient serum using ELISA with D\&G International Inc. kit |
| Secondary | sE-selectin | Change from Baseline to 3 month follow-up | sE-selectin was measured from the patient serum using ELISA with D\&G International Inc. kit |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers6
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05118542
GET https://conductscience.org/api/trials/v1/NCT05118542/registered