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Trial · NCT05134532

Regorafenib After Progression on Atezolizumab Plus Bevacizumab in Advanced HCC

NCT05134532, Phase 2, Unknown, CHA University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Regorafenib After Progression on Atezolizumab Plus Bevacizumab in Advanced HCC. Trials, record NCT05134532. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05134532

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Regorafenib After Progression on Atezolizumab Plus Bevacizumab in Advanced HCC
NCT number
NCT05134532
Status
Unknown
Phases
Phase 2
Enrollment
40 participants, estimated
Lead sponsor
CHA University
Conditions
Hepatocellular Carcinoma
Interventions
regorafenib
First posted
2021-11-26
Last updated
2023-04-26

Source ClinicalTrials.gov

Registered outcomes6

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryProgression-free survival (PFS) by RECIST v 1.1up to 36 monthsthe time from start of study treatment to first documentation of objective tumor progression, or to death due to any cause
SecondaryOverall survivalup to 36 monthsthe time from start of study treatment to date of death due to any cause
SecondaryTime to progression by RECIST v 1.1up to 36 monthsthe time from start of study (Cycle 1 Day 1) to first documentation of objective tumor progression.
SecondaryOverall response rate by RECIST v 1.1up to 36 monthsthe proportion of patients with confirmed complete response or confirmed partial response according to the RECIST v 1.1, relative to the total evaluable patient population.
SecondaryDisease control rate by RECIST v 1.1up to 36 months
the percent of patients with confirmed complete response, partial response, or stable disease for at least 12 weeks on study according to RECIST v 1.1, relative to the total evaluable patient population.
SecondarySafety profiles by NCI-CTCAE version 5up to 36 monthsFor the evaluation of adverse reactions following medication, using NCI-CTCAE version 5

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers13

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
16527888RESULTPubMed
20332205RESULTPubMed
20516446RESULTPubMed
21321535RESULTPubMed
23108136RESULTPubMed
25601652RESULTPubMed
26822708RESULTPubMed
27932229RESULTPubMed
28434648RESULTPubMed
29875066RESULTPubMed

1 to 10 of 13

See all 13 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05134532

GET https://conductscience.org/api/trials/v1/NCT05134532/registered