Trial · NCT05141071
Effect of Ivabradine on Microcirculation and Cardiac Output in Septic Shock Patients
NCT05141071, Phase 2, Completed, Cairo University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effect of Ivabradine on Microcirculation and Cardiac Output in Septic Shock Patients. Trials, record NCT05141071. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05141071
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Ivabradine on Microcirculation and Cardiac Output in Septic Shock Patients
- NCT number
- NCT05141071
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 44 participants, actual
- Lead sponsor
- Cairo University
- Conditions
- Septic Shock
- Interventions
- Ivabradine 5mg Tab, Placebo
- First posted
- 2021-12-02
- Last updated
- 2022-09-01
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Microvascular flow index | 6 hours after administration of Ivabradine or Placebo. | absent (0), intermittent (1), sluggish (2), or normal (3) |
| Secondary | Microvascular flow index | Before drug administration and at 1, 12, and 24 hours thereafter. | absent (0), intermittent (1), sluggish (2), or normal (3) |
| Secondary | Total vessel density | Before drug administration and at 1, 6,12, and 24 hours thereafter. | mm/mm2 |
| Secondary | Percentage of perfused vessels | Before drug administration and at 1, 6,12, and 24 hours thereafter. | Percentage |
| Secondary | Cardiac output | Before drug administration and at 1, 6,12, and 24 hours thereafter. | litres per minute |
| Secondary | Heart rate | Before drug administration and at 1, 6,12, and 24 hours thereafter. | beats per minute |
| Secondary | Central venous saturation | Before drug administration and at 1, 6,12, and 24 hours thereafter. | Percentage |
| Secondary | Central venous-arterial blood carbon dioxide partial pressure difference | Before drug administration and at 1, 6,12, and 24 hours thereafter. | mmHg |
| Secondary | Mean arterial blood pressure | Before drug administration and at 1, 6,12, and 24 hours thereafter. | mmHg |
| Secondary | ICU length of stay | from the date of patient recruitment till the date of discharge from the ICU or the date of death, assessed up to 28 days | Days |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05141071
GET https://conductscience.org/api/trials/v1/NCT05141071/registered