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Trial · NCT05142722

Registered outcomes20

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPercent Change in Low-Density Lipoprotein Cholesterol (LDL-C) From Baseline to Day 84 [PUC]84 Days
LS mean percent change from baseline to Day 84 in Low-Density Lipoprotein Cholesterol (LDL-C) in the obicetrapib group compared to the placebo group \[PUC\]. LDL-C level was measured by preparative ultracentrifugation (PUC).
SecondaryPercent Change in Low Density Lipoprotein-Cholesterol (LDL-C) From Baseline to Day 180 [Martin/Hopkins]180 Days
LS mean percent change from baseline to Day 180 in Low-Density Lipoprotein Cholesterol (LDL-C) in the obicetrapib group compared to the placebo group \[Martin/Hopkins\]. LDL-C value was calculated using the Martin/Hopkins equation unless TG \>= 400 mg/dL or LDL-C \<= 50 mg/dL; where, LDL-C value was measured directly by preparative ultracentrifugation (PUC).
SecondaryPercent Change in Low Density Lipoprotein-Cholesterol (LDL-C) From Baseline to Day 365 [PUC]365 Days
LS mean percent change from baseline to Day 365 in Low-Density Lipoprotein Cholesterol (LDL-C) in the obicetrapib group compared to the placebo group \[PUC\]. LDL-C level was measured by preparative ultracentrifugation (PUC).
SecondaryPercent Change in Apolipoprotein B (ApoB) From Baseline to Day 8484 DaysLS mean percent change from baseline to Day 84 in apolipoprotein B (ApoB) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Apolipoprotein B (ApoB) From Baseline to Day 180180 DaysLS mean percent change from baseline to Day 180 in apolipoprotein B (ApoB) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Apolipoprotein B (ApoB) From Baseline to Day 365365 DaysLS mean percent change from baseline to Day 365 in apolipoprotein B (ApoB) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Non-HDL-C From Baseline to Day 8484 DaysLS mean percent change from baseline to Day 84 in Non-high-density Lipoprotein Cholesterol (Non-HDL-C) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Non-HDL-C From Baseline to Day 180180 DaysLS mean percent change from baseline to Day 180 in Non-high-density Lipoprotein Cholesterol (non-HDL-C) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Non-HDL-C From Baseline to Day 365365 DaysLS mean percent change from baseline to Day 365 in Non-high-density Lipoprotein Cholesterol (non-HDL-C) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in HDL-C From Baseline to Day 8484 DaysLS mean percent change from baseline to Day 84 in High-density Lipoprotein Cholesterol (HDL-C) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in HDL-C From Baseline to Day 180180 DaysLS mean percent change from baseline to Day 180 in High-density Lipoprotein Cholesterol (HDL-C) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in HDL-C From Baseline to Day 365365 DaysLS mean percent change from baseline to Day 365 in High-density Lipoprotein Cholesterol (HDL-C) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Lp(a) From Baseline to Day 8484 DaysLS mean percent change from baseline to Day 84 in Lipoprotein (a) \[Lp(a)\] in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Apolipoprotein A1 (ApoA1) From Baseline to Day 8484 DaysLS mean percent change from baseline to Day 84 in Apolipoprotein A1 (ApoA1) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Total Cholesterol From Baseline to Day 8484 DaysLS mean percent change from baseline to Day 84 in Total Cholesterol (TC) in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Total Cholesterol From Baseline to Day 180180 DaysLS mean percent change from baseline to Day 180 in Total Cholesterol in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Total Cholesterol From Baseline to Day 365365 DaysLS mean percent change from baseline to Day 365 in Total Cholesterol in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Triglycerides From Baseline to Day 8484 DaysLS mean percent change from baseline to Day 84 in Triglycerides in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Triglycerides From Baseline to Day 180180 DaysLS mean percent change from baseline to Day 180 in Triglycerides in obicetrapib group compared to the placebo group.
SecondaryPercent Change in Triglycerides From Baseline to Day 365365 daysLS mean percent change from baseline to Day 365 in Triglycerides in obicetrapib group compared to the placebo group.

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/trials/v1/NCT05142722/registered