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Trial · NCT05151484

Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover

NCT05151484, Phase 4, Active not recruiting, Madhumathi Rao

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover. Trials, record NCT05151484. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05151484

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Novel Precision Medicine Approach to Treatment of Osteoporosis Based on Bone Turnover
NCT number
NCT05151484
Status
Active not recruiting
Phases
Phase 4
Enrollment
60 participants, estimated
Lead sponsor
Madhumathi Rao
Conditions
Age-Related Osteoporosis
Interventions
Teriparatide, Alendronate
First posted
2021-12-09
Last updated
2026-05-14

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryMineral Bone Density of the lumbar spine1 YearPercent change in mineral bone density absolute values of the lumbar spine measured by DXA at baseline and at one year.
PrimaryMeasure of serum osteocalcin levels to predict bone turnover1 Year
Diagnostic Utility of serum osteocalcin level measurements by ELISA at baseline and at one year to predict bone turnover. Area under the receiver operating characteristic curve analysis will be used to determine the discriminative power of osteocalcin levels for determination of low versus non-low bone turnover.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants1

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

ProjectTitlePrincipal investigatorsOrganizationFunderFiscal years
R01AG072797Novel precision medicine approach to treatment of osteoporosis based on bone turnoverRAO, MADHUMATHIUNIVERSITY OF KENTUCKYNATIONAL INSTITUTE ON AGING2021 to 2025

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05151484

GET https://conductscience.org/api/trials/v1/NCT05151484/registered