Trial · NCT05167825
Outcomes45
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
1 to 20 of 45
Download this page as JSON| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Fold Change From Baseline at Week 24 in Pulmonary Vascular Resistance Index (PVRI) | Baseline (Day 1), Week 24 | Efficacy analysis set included all participants who were administered at least 1 dose of macitentan. | Fold change (percentage) | GEOMETRIC_MEAN |
| SECONDARY | Change From Baseline at Week 24 in Hemodynamic Variables: Pulmonary Vascular Resistance (PVR) | Baseline (Day 1), Week 24 | |||
| SECONDARY | Change From Baseline in Mean Right Atrial Pressure (mRAP) | Baseline (Day 1), Week 24 | |||
| SECONDARY | Change From Baseline at Week 24 in Hemodynamic Variables: Mean Pulmonary Arterial Pressure (mPAP) | Baseline (Day 1), Week 24 | |||
| SECONDARY | Change From Baseline at Week 24 in Hemodynamic Variables: Cardiac Index (CI) | Baseline (Day 1), Week 24 | |||
| SECONDARY | Change From Baseline at Week 24 in Hemodynamic Variables: Cardiac Output (CO) | Baseline (Day 1), Week 24 | |||
| SECONDARY | Change From Baseline at Week 24 in Hemodynamic Variables: Total Pulmonary Resistance (TPR) | Baseline (Day 1), Week 24 | |||
| SECONDARY | Change From Baseline at Week 24 in Hemodynamic Variables: Mixed Venous Oxygen Saturation (SvO2) | Baseline (Day 1), Week 24 | |||
| SECONDARY | Number of Participants With Change From Baseline at Weeks 4, 8, 12, 16, 20, 24, 28, 40, and 52 in World Health Organization (WHO) Functional Class (FC) | Weeks 4, 8, 12, 16, 20, 24, 28, 40, 52 | |||
| SECONDARY | Number of Participants With Change From Baseline at Weeks 4, 8, 12, 16, 20, 24, 28, 40, and 52 in Panama FC | Weeks 4, 8, 12, 16, 20, 24, 28, 40, 52 | |||
| SECONDARY | Change From Baseline to Weeks 24 and 52 in 6-minute Walk Distance (6MWD) as Measured by the 6-minute Walk Test (6MWT) | Baseline (Day 1), Weeks 24 and 52 | |||
| SECONDARY | Change From Baseline to Week 12, 24, 28, 40, and 52 in N-terminal Pro-Brain Natriuretic Peptide (NT-proBNP) | Baseline (Day 1), Week 12, 24, 28, 40, and 52 | |||
| SECONDARY | Change From Baseline at Weeks 12, 24, and 52 in Tricuspid Annular Plane Systolic Excursion (TAPSE) | Baseline (Day 1), Weeks 12, 24, and 52 | |||
| SECONDARY | Change From Baseline at Week 12, 24, and 52 in Left Ventricular Eccentricity Index (LVEI) | Baseline (Day 1), Weeks 12, 24 and 52 | |||
| SECONDARY | Change From Baseline to Week 12, 24, and 52 in Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core Scales Short Form (SF-15) | Baseline (Day 1), Weeks 12, 24, and 52 | |||
| SECONDARY | Change From Baseline to Weeks 12, 24, and 52 in Physical Activity as Measured by Accelerometry: Number of Hours of Daytime Activity | Baseline (Day 1), Weeks 12, 24, and 52 | |||
| SECONDARY | Change From Baseline to Weeks 12, 24, and 52 in Physical Activity as Measured by Accelerometry: Mean Count Per Minute of Daily Activity | Baseline (Day 1), Weeks 12, 24, and 52 | |||
| SECONDARY | Change From Baseline to Weeks 12, 24, and 52 in Physical Activity as Measured by Accelerometry: Mean Daily Time Spent in Light Physical Activity | Baseline (Day 1), Weeks 12, 24, and 52 | |||
| SECONDARY | Change From Baseline to Weeks 12, 24, and 52 in Physical Activity as Measured by Accelerometry: Mean Daily Time Spent in Moderate to Vigorous Physical Activity | Baseline (Day 1), Weeks 12, 24, and 52 | |||
| SECONDARY | Change From Baseline to Week 24 and Week 52 in Borg Dyspnea Index | Baseline (Day 1), Weeks 24 and 52 |
Source ClinicalTrials.govtrials-2026-11-12-0.4.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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GET https://conductscience.org/api/trials/v1/NCT05167825/outcomes