Computerized Cognitive Rehabilitation of Executive Deficits in Stroke Patients
NCT05169632, Not applicable, Unknown, Centre Hospitalier Universitaire Vaudois
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Computerized Cognitive Rehabilitation of Executive Deficits in Stroke Patients | ClinicalTrials.gov |
| NCT number | NCT05169632 | ClinicalTrials.gov |
| Status | Unknown | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 32 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Centre Hospitalier Universitaire Vaudois | ClinicalTrials.gov |
| Conditions | Stroke, Executive Dysfunction | ClinicalTrials.gov |
| Interventions | Computerized Gaming Rehabilitation Program 1, Computerized Gaming Rehabilitation Program 2 | ClinicalTrials.gov |
| First posted | 2021-12-27 | ClinicalTrials.gov |
| Last updated | 2024-08-13 | ClinicalTrials.gov |
Registered outcomes 27
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change in cognitive interference after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Cognitive interference is measured using the Delis-Kaplan Executive Function System (D-KEFS; Delis, Kaplan, Kramer, 2001) Stroop Test | ClinicalTrials.gov |
| Primary | Change in divided attention after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Divided attention is measured using the Test of Attentional Performance (TAP, version 2.3.1; Zimmermann and Fimm, 2002) subtest for divided attention | ClinicalTrials.gov |
| Primary | Change in visuospatial short term memory after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Visuospatial short term memory is measured by the immediate recall of the Brief Visuospatial Memory Test-Revised (BVMT-R; Benedict, 1996) | ClinicalTrials.gov |
| Primary | Change in subjective executive function after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Subjective executive function is measured by the Working Memory Questionnaire (WMQ; Vallat-Azouvi et al, 2012; 30 items, participants rate 10 statements on storage, attention and executive domain on a Likert-scale from 1-5 (not at all - extremely)) | ClinicalTrials.gov |
| Secondary | Change in visual working memory after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Visual working memory will be assessed via performance on the computerized 'Filter task' (Vogel, 2005). | ClinicalTrials.gov |
| Secondary | Change in design fluency after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | The Five-Point Test (Regard, 1982) will be used to assess design fluency. | ClinicalTrials.gov |
| Secondary | Change in processing speed after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | The Trail-Making-Test Part A (Reitan, 1955) will be used to assess processing speed. | ClinicalTrials.gov |
| Secondary | Change in cognitive flexibility assessed by the TMT-B after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Cognitive flexibility will be measured using the Trail-Making-Test B (TMT-B; Reitan, 1955). | ClinicalTrials.gov |
| Secondary | Change in cognitive flexibility assessed by the TAP Flexibility after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Cognitive flexibility will be measured using the subscale 'Flexibility' of the Test of Attentional Performance (TAP, version 2.3.1; Zimmermann and Fimm, 2002) | ClinicalTrials.gov |
| Secondary | Change in cognitive inhibition after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | The Test of Attentional Performance (TAP, version 2.3.1; Zimmermann and Fimm, 2002) subtest Go/NoGo will assess cognitive inhibition. | ClinicalTrials.gov |
| Secondary | Change in cognitive multitasking after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | A subtest of a custom-made tablet-based cognitive evaluation tool will measure cognitive multitasking. | ClinicalTrials.gov |
| Secondary | Change in covert shift of attention after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Measured by the corresponding subtest of the Test of Attentional Performance (TAP, version 2.3.1; Zimmermann and Fimm, 2002). | ClinicalTrials.gov |
| Secondary | Change in risk of falls and postural stability after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Postural stability and risk of falls will be assessed using the BTrackS Balance Plate (FDA registered class 1 medical device #3010668481) | ClinicalTrials.gov |
| Secondary | Change in dynamic stability after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Dynamic stability will be assessed by the Four Square Step Test (FSST; Dite et al, 2002), which tests the participant's ability to step over objects forwards, sideways and backwards; the movements of the FSST are comparable to the ones implemented in the training program. | ClinicalTrials.gov |
| Secondary | Change in ability to perform a cognitive and physical dual task after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | In order to assess cognitive and motor dual task ability, the study participant will perform the 'Timed Up and Go Cognitive' subtest from the MiniBESTest (Franchignoni et al, 2010). | ClinicalTrials.gov |
| Secondary | Change in heart rate after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Heart rate (HR) will be recorded at rest in supine position during a 5-minute window using a chest belt. | ClinicalTrials.gov |
| Secondary | Change in heart rate variability after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Heart rate variability (HRv) will be recorded at rest in supine position during a 5-minute window using a chest belt. | ClinicalTrials.gov |
| Secondary | Change in systolic and diastolic blood pressure after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Determined by the mean of three blood pressure measurements using a sphygmomanometer and a stethoscope. | ClinicalTrials.gov |
| Secondary | Everyday physical activity during 6-week training period. | 6 weeks | Measuring daily step count and minutes of daily activity using a wrist-attached wearable device will determine everyday physical acitivity during the training period. | ClinicalTrials.gov |
| Secondary | Change in everyday life quality after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2) | 6 weeks | Study participants will rate everyday life quality using the Quality of Life after Brain Injury questionnaire (QOLIBRI; von Steinbuchel, 2010; 36 items originally, adapted to 35 items for stroke, participants rate applicability of statements on quality of life after stroke from not at all to very)) | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 14
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 2229948 | BACKGROUND | PubMed |
| 6880820 | BACKGROUND | PubMed |
| 7126941 | BACKGROUND | PubMed |
| 7162920 | BACKGROUND | PubMed |
| 12422327 | BACKGROUND | PubMed |
| 13263471 | BACKGROUND | PubMed |
| 15012851 | BACKGROUND | PubMed |
| 16306992 | BACKGROUND | PubMed |
| 20210602 | BACKGROUND | PubMed |
| 20461334 | BACKGROUND | PubMed |
| 22537095 | BACKGROUND | PubMed |
| 23378841 | BACKGROUND | PubMed |
| 24453758 | BACKGROUND | PubMed |
| 24972546 | BACKGROUND | PubMed |
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 5
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Design Fluency Test | Secondary outcome | ConductCognition |
| Go/No-Go Task | Secondary outcome | ConductCognition |
| Trail Making Test A | Secondary outcome | ConductCognition |
| Trail Making Test B | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)