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Trial · NCT05199311

Carfilzomib, Iberdomide (CC-220) and Dexamethasone (KID) in Transplant Eligible Multiple Myeloma

NCT05199311, Phase 1, Phase 2, Suspended, Hackensack Meridian Health

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Carfilzomib, Iberdomide (CC-220) and Dexamethasone (KID) in Transplant Eligible Multiple Myeloma. Trials, record NCT05199311. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05199311

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Carfilzomib, Iberdomide (CC-220) and Dexamethasone (KID) in Transplant Eligible Multiple Myeloma
NCT number
NCT05199311
Status
Suspended
Phases
Phase 1, Phase 2
Enrollment
66 participants, estimated
Lead sponsor
Hackensack Meridian Health
Conditions
Multiple Myeloma
Interventions
Carfilzomib, Iberdomide, Oral Dexamethasone
First posted
2022-01-20
Last updated
2026-07-13

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryRate of treatment emergent adverse events (TEAEs)Measured after cycle 4 of induction KID (each cycle is 28 days)Rate of patients with treatment emergent adverse events (TEAEs) overall and per dose level
PrimaryCR and sCRMeasured after cycle 4 of induction KID (each cycle is 28 days)Evaluation of the rate of complete remission (CR) + stringent complete (sCR) remission for patients receiving 2-4 cycles of the combination of KID followed by ASCT in patients with newly diagnosed MM.
SecondaryOverall Response Rate (ORR)
Participants will be followed for response assessment every 28 days until progression of disease or a subsequent myeloma regimen has been started. On treatment study duration will last up to 12 months; Post treatment follow up will last up to two years.
Assessment of overall response rate (ORR) of newly diagnosed transplant-eligible MM patients.
SecondaryProgression Free Survival (PFS)
Participants will be followed for response assessment every 28 days until progression of disease or a subsequent myeloma regimen has been started. On treatment study duration will last up to 12 months; Post treatment follow up will last up to two years.
Assessment of progression-free survival (PFS) of newly diagnosed transplant-eligible MM patients.
SecondaryOverall Survival (OS)
Participants will be followed for response assessment every 28 days until progression of disease or a subsequent myeloma regimen has been started. On treatment study duration will last up to 12 months; Post treatment follow up will last up to two years.
Assessment of overall survival (OS) of newly diagnosed transplant-eligible MM patients.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers78

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
7165009BACKGROUNDPubMed
8165126BACKGROUNDPubMed
8433390BACKGROUNDPubMed
11418482BACKGROUNDPubMed
12826635BACKGROUNDPubMed
14512299BACKGROUNDPubMed
15958804BACKGROUNDPubMed
16470606BACKGROUNDPubMed
16840727BACKGROUNDPubMed
17327405BACKGROUNDPubMed

1 to 10 of 78

See all 78 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05199311

GET https://conductscience.org/api/trials/v1/NCT05199311/papers?page=2