Trial · NCT05228041
BIOlogics in Severe Nasal POlyposis SurvEy
NCT05228041, Active not recruiting, University Hospital, Lille
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. BIOlogics in Severe Nasal POlyposis SurvEy. Trials, record NCT05228041. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05228041
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- BIOlogics in Severe Nasal POlyposis SurvEy
- NCT number
- NCT05228041
- Status
- Active not recruiting
- Enrollment
- 100 participants, estimated
- Lead sponsor
- University Hospital, Lille
- Conditions
- Chronic Rhinosinusitis With Nasal Polyps
- Interventions
- Biologic treatments available in CRSwNP (dupilumab, mepolizumab and benralizumab according to their marketing approval)
- First posted
- 2022-02-08
- Last updated
- 2026-04-29
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 6-month rate of patients with a SNOT-22 (Sinonasal Outcome test -22) score change over the minimal clinically important difference of 8.9 by comparison of SNOT-22 scores measured at Month 0 and Month 6 | Day0, Month 6 | from 0 to 110 , 110 = worst outcome |
| Secondary | SNOT 22 (Sinonasal Outcome Test-22) scores | Day 0, Month 3, Month 6, Month 12 and Month 18 | from 0 to 110 , 110 = worst outcome |
| Secondary | Visual analogical scale (VAS) for nasal obstruction | Day 0, Month 3, Month 6, Month 12 and Month 18 | from 0 to 10, 10 = worst outcome |
| Secondary | Visual analogical scale (VAS) for smell lost | Day 0, Month 3, Month 6, Month 12 and Month 18 | from 0 to 10, 10 = worst outcome |
| Secondary | Visual analogical scale (VAS) for rhinorrhea | Day 0, Month 3, Month 6, Month 12 and Month 18 | from 0 to 10, 10 = worst outcome |
| Secondary | Visual analogical scale (VAS) for craniofacial pain | Day 0, Month 3, Month 6, Month 12 and Month 18 | from 0 to 10, 10 = worst outcome |
| Secondary | Number of systemic corticosteroid treatment courses between each visit | Day 0, Month 3, Month 6, Month 12 and Month 18 | number of treatment sequencies |
| Secondary | Delay to first surgical procedure | Day 0, Month 3, Month 6, Month 12 and Month 18 | time between biologic onset and need for surgery |
| Secondary | Blood eosinophil count | Day 0, Month 3, Month 6, Month 12 and Month 18 | number of cells per mm3 |
| Secondary | Blood total IgE concentrations | Day 0, Month 3, Month 6, Month 12 and Month 18 | concentration expressed by KUI/L |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 38749694 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05228041
GET https://conductscience.org/api/trials/v1/NCT05228041/registered