Trial · NCT05247528
Safety And Tolerability Of Subcutaneous MANP In Difficult To Control/Resistant Hypertensive Subjects
NCT05247528, Phase 1, Completed, E-Star BioTech, LLC
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Safety And Tolerability Of Subcutaneous MANP In Difficult To Control/Resistant Hypertensive Subjects. Trials, record NCT05247528. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05247528
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Safety And Tolerability Of Subcutaneous MANP In Difficult To Control/Resistant Hypertensive Subjects
- NCT number
- NCT05247528
- Status
- Completed
- Phases
- Phase 1
- Enrollment
- 37 participants, actual
- Lead sponsor
- E-Star BioTech, LLC
- Conditions
- Resistant Hypertension, Difficult to Control Hypertension
- Interventions
- MANP, Placebo
- First posted
- 2022-02-21
- Last updated
- 2022-11-29
Source ClinicalTrials.gov
Registered outcomes39
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Adverse Events | through study completion, an average of 2 months. | Number and percent of participants with one or more Treatment Emergent Adverse Events (TEAEs) or any serious adverse events (SAEs). |
| Primary | Blood Pressure | From baseline to Days 1-6, Day 12, and 21. | Change in SBP and DBP |
| Primary | Hematology Hematocrit | From baseline to Day 21. | Change in Percent Hematocrit |
| Primary | Physical Examination: Body Parts | From baseline to Day 21 | Change in investigator assessment of the condition of body parts (head, throat, abdomen, and extremities) |
| Primary | ECG: QT interval | From baseline to Days 1-6 and Day 21. | Change in 12-Lead ECG QT Interval |
| Primary | Temperature | From baseline to Days 1-6, Day 12, and 21. | Change in Temperature |
| Primary | Pulse Rate | From baseline to Days 1-6, Day 12, and 21. | Change in Pulse Rate |
| Primary | Hematology: Hemoglobin | From baseline to Day 21 | Change in g/dL Hemoglobin |
| Primary | Hematology: Mean Corpuscular Hemoglobin | From baseline to Day 21 | Change in the mean corpuscular hemoglobin. |
| Primary | Hematology: Platelets | From baseline to Day 21 | Change in platelet count |
1 to 10 of 39Source ClinicalTrials.gov
See all 39 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05247528
GET https://conductscience.org/api/trials/v1/NCT05247528/registered?page=2