Trial · NCT05251181
A Study to Assess Safety and Efficacy of Centhaquine as a Resuscitative Agent
NCT05251181, Phase 3, Not yet recruiting, Pharmazz, Inc.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Study to Assess Safety and Efficacy of Centhaquine as a Resuscitative Agent. Trials, record NCT05251181. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05251181
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study to Assess Safety and Efficacy of Centhaquine as a Resuscitative Agent
- NCT number
- NCT05251181
- Status
- Not yet recruiting
- Phases
- Phase 3
- Enrollment
- 430 participants, estimated
- Lead sponsor
- Pharmazz, Inc.
- Conditions
- Hypovolemic Shock
- Interventions
- Normal Saline, Centhaquine
- First posted
- 2022-02-22
- Last updated
- 2026-09-17
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Proportion of subjects with all-cause mortality [Time frame: Day 0 through day 28]. | Day 0 through day 28 | Incidence of mortality |
| Secondary | Proportion of subjects with all-cause mortality within 48 hours | 48 hours | Proportion of subjects with all-cause mortality within 48 hours |
| Secondary | Change in Mean Arterial Pressure (MAP) from baseline of at least 10 mm Hg; Mean through 48 hours and at the time of discharge or day 7 | First 48 hours and at the time of discharge or day 7 | Change in Mean Arterial Pressure (MAP) from baseline of at least 10 mm Hg; Mean through 48 hours and at the time of discharge or day 7 |
| Secondary | Time (hours) to decrease blood lactate level to <2 mmol/L | 48 hours | Time (hours) to decrease blood lactate level to \<2 mmol/L; Mean through 2 hours for the first 12 hours, then every 6 hours for the next 36 hours. |
| Secondary | Proportion of patients with adverse events (AEs) and serious adverse events (SAEs) | Day 0 through day 28 | Proportion of patients with adverse events (AEs) and serious adverse events (SAEs) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers15
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05251181
GET https://conductscience.org/api/trials/v1/NCT05251181/registered