Trial · NCT05290090
ZR2 Followed by Immunochemotherapy in Elderly Patients With Newly-diagnosed DLBCL
NCT05290090, Phase 2, Unknown, Zhejiang Cancer Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. ZR2 Followed by Immunochemotherapy in Elderly Patients With Newly-diagnosed DLBCL. Trials, record NCT05290090. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05290090
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- ZR2 Followed by Immunochemotherapy in Elderly Patients With Newly-diagnosed DLBCL
- NCT number
- NCT05290090
- Status
- Unknown
- Phases
- Phase 2
- Enrollment
- 31 participants, estimated
- Lead sponsor
- Zhejiang Cancer Hospital
- Conditions
- Diffuse Large B Cell Lymphoma
- Interventions
- Rituximab, Lenalidomide, Zanubrutinib and RCHOP
- First posted
- 2022-03-22
- Last updated
- 2023-10-17
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | ORR | 21days after the end of treatment | overall response rate |
| Secondary | PFS | From date of first day of treatment until the date of first documented progression, assessed up to 24 months | Progression Free Survival |
| Secondary | OS | From date of first day of treatment until the date of first documented date of death from any cause, assessed up to 24 months | Overall Survival |
| Secondary | AE and SAE | From date of first day of treatment until 30 day after last treatment | Adverse event and serious adverse event |
| Secondary | Performance status | At screening period, after 2 cycles of ZR2 regimen(each cycle is 21 days), after 2 cycles of RCHOP regimen(each cycle is 21 days) and 21days after the end of treatment | Assess the patient's performance status according to the Barthel index. Patients will be classified into 5 scales with the score ranging from 0 to 100: 0-20 points=extremely severe functional impairment; 25-45 points=severe functional impairment; 50-70 points=moderate functional impairment; 75-95 points=mild functional impairment; 100 points=normal. Higher scores mean a better outcome. |
| Secondary | Life quality | At screening period, after 2 cycles of ZR2 regimen(each cycle is 21 days), after 2 cycles of RCHOP regimen(each cycle is 21 days) and 21days after the end of treatment | Assess the patient's quality of life according to the EORTC QLQ-C30 questionnaire. Higher scores mean a worse outcome. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05290090
GET https://conductscience.org/api/trials/v1/NCT05290090/registered