Trial · NCT05308732
Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy
NCT05308732, Phase 1, Completed, Instituto Nacional de Cancer, Brazil
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy. Trials, record NCT05308732. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05308732
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy
- NCT number
- NCT05308732
- Status
- Completed
- Phases
- Phase 1
- Enrollment
- 20 participants, actual
- Lead sponsor
- Instituto Nacional de Cancer, Brazil
- Conditions
- Head and Neck Neoplasms, Mucositis Oral, Radiotherapy; Complications
- Interventions
- Copaiba
- First posted
- 2022-04-04
- Last updated
- 2026-10-13
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Maximum tolerated dose | Through the use of the copaiba oil, an average of 6 to 7 weeks. | Evaluate the maximum tolerated dose of the aqueous copaiba solution. |
| Secondary | Acess rate of pain | From baseline to the last day of copaiba use (day 33 to day 37). | Assess the level of pain of the patients during the mouthwash with the aqueous copaiba solution through the visual analog pain scale (classified between 0 to 10, when a higher score means worst level of pain) |
| Secondary | Acess rate of oral pain | From baseline to the last day of copaiba use (day 33 to day 37). | Assess the level of pain of the patients during the mouthwash with the aqueous copaiba solution through the criteria proposed by the Common Terminology Criteria for Adverse Events (CTCAE) v 5.0.(classified between grades 1 to 3, when a higher score means worst level of pain) |
| Secondary | Incidence of Oral Mucositis | From baseline to the last day of copaiba use (day 33 to day 37). | Check the incidence of oral mucositis in the treated and untreated areas with low power laser. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers44
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT05308732
GET https://conductscience.org/api/trials/v1/NCT05308732/papers?page=2