The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study
NCT05314634, Not applicable, Completed, National Taiwan Normal University; results first posted 2025-02-20
Trial 11
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | The Effect of Acute Concurrent Exercise on Executive Function: An Event-Related Potential Study | ClinicalTrials.gov |
| NCT number | NCT05314634 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 78 participants, actual | ClinicalTrials.gov |
| Lead sponsor | National Taiwan Normal University | ClinicalTrials.gov |
| Conditions | Executive Function | ClinicalTrials.gov |
| Interventions | concurrent exercise, aerobic exercise | ClinicalTrials.gov |
| First posted | 2022-04-06 | ClinicalTrials.gov |
| Last updated | 2025-02-20 | ClinicalTrials.gov |
| Results first posted | 2025-02-20 | ClinicalTrials.gov |
Registered outcomes 3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Task Switch Test Response Times | 30 minutes | The shifting aspect of executive function was assessed using a computerised task-switching test. Each participant (N=78) completed 384 trials across six blocks (64 trials per block). The test consisted of two types of cognitive tasks: (1) number magnitude judgment (greater/less than 5) for digits 1-9 presented in solid-line squares, and (2) odd/even judgment for numbers presented in dotted-line squares. Performance was analysed by calculating each participant's mean response time (milliseconds) under four conditions: Homogeneous condition: Blocks where participants performed the same task repeatedly (Blocks 1 \& 2, e.g., AAAA or BBBB) Heterogeneous condition: Blocks where tasks were mixed (Blocks 3-6, e.g., AABBAA) Non-switch trials: Consecutive trials of the same task type within heterogeneous blocks (e.g., AA or BB) Switch trials: Trials where the task changed from the previous trial within heterogeneous blocks (e.g., AB or BA) Lower response time represents better task perform | ClinicalTrials.gov |
| Other | Blood Lactate | before intervention, 17 minutes after intervention, and immediately after the 35 minute intervention | The lactic acid system is one of the important systems of human energy metabolism. In addition to supplying energy to muscles, it can also be used as an energy source for brain energy metabolism. When people doing exercise, the concentration of blood lactate will be increased, and the lactate acid system will replace the glucose system as the main energy source for the brain. In the present study, blood lactate were collected from fingertip with a lancet and measured by lactate analyzer before, 17 minutes after, and after intervention. | ClinicalTrials.gov |
| Other | Stroop Task | 30 minutes | The Stroop task consists of neutral, congruent, and incongruent trials. In neutral trials, colored rectangles were presented and participants were instructed to respond to whether the squares were red, blue, or green. For congruent and incongruent trials, participants were presented with the names of the three Chinese color words of 紅 (red), 藍 (blue), or 綠 (green) printed in either the same (congruent) or different (incongruent) ink color and instructed to respond to the color of the ink while inhibiting the meaning of the word. | ClinicalTrials.gov |
Outcomes 3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|---|---|---|---|---|---|
| PRIMARY | Task Switch Test Response Times | 30 minutes | The analysis was based on participants' mean response times under four cognitive conditions (Homogeneous, Heterogeneous, Non-switch, and Switch), derived from their performance across 384 trials (6 blocks × 64 trials). | millisecond | MEAN | ClinicalTrials.gov |
| OTHER_PRE_SPECIFIED | Blood Lactate | before intervention, 17 minutes after intervention, and immediately after the 35 minute intervention | Blood lactate samples were collected from fingertip with a lancet and measured by lactate analyzer at three time points: before, 17 minutes after, and after intervention (three blood samples were collected from each participant). | mmol/l | MEAN | ClinicalTrials.gov |
| OTHER_PRE_SPECIFIED | Stroop Task | 30 minutes | Given temporal constraints, the Stroop task was not measured in this study. | ClinicalTrials.gov |
Results by group 21
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|---|---|---|---|---|---|
| Task Switch Test Response Times | Concurrent Exercise Group, CE | Heterogeneous | 783.97 | Standard Error 11.65 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Aerobic Exercise Group, AE | Heterogeneous | 788.76 | Standard Error 11.66 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Reading Control Group, RC | Heterogeneous | 839.46 | Standard Error 11.65 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Concurrent Exercise Group, CE | Homogeneous | 566.46 | Standard Error 14.67 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Aerobic Exercise Group, AE | Homogeneous | 547.82 | Standard Error 14.70 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Reading Control Group, RC | Homogeneous | 618.30 | Standard Error 14.72 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Concurrent Exercise Group, CE | Non-switch | 737.73 | Standard Error 11.63 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Aerobic Exercise Group, AE | Non-switch | 753.98 | Standard Error 11.62 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Reading Control Group, RC | Non-switch | 797.48 | Standard Error 11.62 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Concurrent Exercise Group, CE | Switch | 833.32 | Standard Error 13.34 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Aerobic Exercise Group, AE | Switch | 825.39 | Standard Error 13.34 | millisecond | ClinicalTrials.gov |
| Task Switch Test Response Times | Reading Control Group, RC | Switch | 882.18 | Standard Error 13.34 | millisecond | ClinicalTrials.gov |
| Blood Lactate | Concurrent Exercise Group, CE | Before intervention | 2.95 | Standard Error 0.32 | mmol/l | ClinicalTrials.gov |
| Blood Lactate | Aerobic Exercise Group, AE | Before intervention | 3.09 | Standard Error 0.32 | mmol/l | ClinicalTrials.gov |
| Blood Lactate | Reading Control Group, RC | Before intervention | 2.4 | Standard Error 0.32 | mmol/l | ClinicalTrials.gov |
| Blood Lactate | Concurrent Exercise Group, CE | Seventeen minutes after intervention | 5.58 | Standard Error 0.41 | mmol/l | ClinicalTrials.gov |
| Blood Lactate | Aerobic Exercise Group, AE | Seventeen minutes after intervention | 5.27 | Standard Error 0.41 | mmol/l | ClinicalTrials.gov |
| Blood Lactate | Reading Control Group, RC | Seventeen minutes after intervention | 2.13 | Standard Error 0.41 | mmol/l | ClinicalTrials.gov |
| Blood Lactate | Concurrent Exercise Group, CE | After intervention | 8.94 | Standard Error 0.44 | mmol/l | ClinicalTrials.gov |
| Blood Lactate | Aerobic Exercise Group, AE | After intervention | 4.65 | Standard Error 0.44 | mmol/l | ClinicalTrials.gov |
Participant flow 9
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|---|---|---|---|---|
| Overall Study | STARTED | Concurrent Exercise Group, CE | 26 | ClinicalTrials.gov | |
| Overall Study | STARTED | Aerobic Exercise Group, AE | 26 | ClinicalTrials.gov | |
| Overall Study | STARTED | Reading Control Group, RC | 26 | ClinicalTrials.gov | |
| Overall Study | COMPLETED | Concurrent Exercise Group, CE | 26 | ClinicalTrials.gov | |
| Overall Study | COMPLETED | Aerobic Exercise Group, AE | 26 | ClinicalTrials.gov | |
| Overall Study | COMPLETED | Reading Control Group, RC | 26 | ClinicalTrials.gov | |
| Overall Study | NOT COMPLETED | Concurrent Exercise Group, CE | 0 | ClinicalTrials.gov | |
| Overall Study | NOT COMPLETED | Aerobic Exercise Group, AE | 0 | ClinicalTrials.gov | |
| Overall Study | NOT COMPLETED | Reading Control Group, RC | 0 | ClinicalTrials.gov |
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 9
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|---|---|---|---|
| Total, all-cause mortality | Concurrent Exercise Group, CE | 0 | 26 | ClinicalTrials.gov |
| Total, all-cause mortality | Aerobic Exercise Group, AE | 0 | 26 | ClinicalTrials.gov |
| Total, all-cause mortality | Reading Control Group, RC | 0 | 26 | ClinicalTrials.gov |
| Total, other adverse events | Concurrent Exercise Group, CE | 0 | 26 | ClinicalTrials.gov |
| Total, other adverse events | Aerobic Exercise Group, AE | 0 | 26 | ClinicalTrials.gov |
| Total, other adverse events | Reading Control Group, RC | 0 | 26 | ClinicalTrials.gov |
| Total, serious adverse events | Concurrent Exercise Group, CE | 0 | 26 | ClinicalTrials.gov |
| Total, serious adverse events | Aerobic Exercise Group, AE | 0 | 26 | ClinicalTrials.gov |
| Total, serious adverse events | Reading Control Group, RC | 0 | 26 | ClinicalTrials.gov |
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Task Switching Test | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Other outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)