Trial · NCT05327296
Outcomes14
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
1 to 14 of 14
Download this page as JSON| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Percentage of Time Sedation Depth is Maintained Within the Target Range, in Absence of Rescue Sedation, as Assessed According to the RASS Scale, in Isoflurane- vs Propofol-treated Patients | From start to end of study treatment (up to 48 (±6) hours) | This Outcome Measure was pre-specified to only assess the Randomized participants (i.e., not Run-in participants) | percentage of time | MEAN |
| SECONDARY | Key Secondary: The Effect of Isoflurane vs Propofol on Use of Opioids During the Study Treatment Period | From 60 minutes prior to Baseline until end of study treatment (60 minutes + up to 48 (±6) hours) | This Outcome Measure was pre-specified to only assess the Randomized participants (i.e., not Run-in participants) | µg/kg/hr fentanyl equivalents | MEAN |
| SECONDARY | Key Secondary: The Effect of Isoflurane vs Propofol on the Wake up Time at End of Study Drug Treatment | Up to 4 hours after stop of study drug treatment (up to 54 (±6) hours) | This Outcome Measure was pre-specified to only assess the Randomized participants (i.e., not Run-in participants) | minutes | MEDIAN |
| SECONDARY | Key Secondary: The Effect of Isoflurane vs Propofol on Cognitive Recovery After End of Study Drug Treatment | At 60 minutes (±10 minutes) after end of study drug treatment (up to 49 (±6) hours) | This Outcome Measure was pre-specified to only assess the Randomized participants (i.e., not Run-in participants) | Participants | COUNT_OF_PARTICIPANTS |
| SECONDARY | Key Secondary: The Effect of Isoflurane vs Propofol on Spontaneous Breathing Effort During the Study Drug Treatment Period | From start to end of study treatment, up to 48 (±6) hours | This Outcome Measure was pre-specified to only assess the Randomized participants (i.e., not Run-in participants) | % of observations | MEAN |
| SECONDARY | Other Secondary: The Effect of Isoflurane vs Propofol on Time From Sedation Termination to Extubation in Patients for Whom Study Drug is Terminated for Extubation | From end of study drug treatment to extubation (up to 7 Days after randomization) | This Outcome Measure was pre-specified to only assess the Randomized participants (i.e., not Run-in participants) | Time to extubation (minutes) | MEDIAN |
| SECONDARY | Other Secondary: The Effect of Isoflurane vs Propofol on Days Alive and Free of Mechanical Ventilation Through Study Day 30 | From start of study treatment up to 30 days | This Outcome Measure was pre-specified to only assess the Randomized participants (i.e., not Run-in participants) | Days | LEAST_SQUARES_MEAN |
| SECONDARY | Other Secondary: To Compare the Effect of Isoflurane vs Propofol on Days Alive and Free of the ICU | From start of study treatment up to 30 days | This Outcome Measure was pre-specified to only assess the Randomized participants (i.e., not Run-in participants) | Days | LEAST_SQUARES_MEAN |
| SECONDARY | Other Secondary: The Effect of Isoflurane vs Propofol on Delirium and Coma Free Days Until 7 Days After End of Study Treatment | From start of study treatment until 7 days after end of treatment (up to 9 days post study drug treatment initiation) | This Outcome Measure was pre-specified to be assess based on the Safety Population (run-in patients and Randomized participants that received any study drug) | Days | MEAN |
| SECONDARY | Other Secondary: The Effect of Isoflurane vs Propofol on Mortality at 30 Days After Randomization | At 30 days after randomization | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Other Secondary: The Effect of Isoflurane vs Propofol on Mortality at 3 Months After Randomization | At 3 months after randomization | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Other Secondary: The Effect of Isoflurane vs Propofol on Mortality at 6 Months After Randomization | At 6 months after randomization | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Other Secondary: Sedaconda ACD-S Device Deficiencies in Patients Receiving Isoflurane | From start to end of study treatment (up to 48 (±6) hours) | This Outcome Measure was pre-specified to be assess based on the Safety Population (run-in patients and Randomized participants that received any study drug) | Device Deficiencies | NUMBER |
| SECONDARY | Other Secondary: The Use of Restraints in Patients Receiving Isoflurane vs Propofol | From start to end of study treatment (up to 48 (±6) hours) | This Outcome Measure was pre-specified to be assess based on the Safety Population (run-in patients and Randomized participants that received any study drug) | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT05327296/outcomes