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Trial · NCT05327296

Results by group31

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage of Time Sedation Depth is Maintained Within the Target Range, in Absence of Rescue Sedation, as Assessed According to the RASS Scale, in Isoflurane- vs Propofol-treated PatientsIsoflurane72Standard Deviation 26.6percentage of time
Percentage of Time Sedation Depth is Maintained Within the Target Range, in Absence of Rescue Sedation, as Assessed According to the RASS Scale, in Isoflurane- vs Propofol-treated PatientsPropofol73.7Standard Deviation 29.15percentage of time
Key Secondary: The Effect of Isoflurane vs Propofol on Use of Opioids During the Study Treatment PeriodIsoflurane-0.29Standard Deviation 0.91µg/kg/hr fentanyl equivalents
Key Secondary: The Effect of Isoflurane vs Propofol on Use of Opioids During the Study Treatment PeriodPropofol0.03Standard Deviation 0.601µg/kg/hr fentanyl equivalents
Key Secondary: The Effect of Isoflurane vs Propofol on the Wake up Time at End of Study Drug TreatmentIsoflurane13.0Inter-Quartile Range 5.0 to 50.0minutes
Key Secondary: The Effect of Isoflurane vs Propofol on the Wake up Time at End of Study Drug TreatmentPropofol17.0Inter-Quartile Range 7.0 to 30.0minutes
Key Secondary: The Effect of Isoflurane vs Propofol on Cognitive Recovery After End of Study Drug TreatmentIsofluraneNo Delirium (CAM-ICU7 0-2)20Participants
Key Secondary: The Effect of Isoflurane vs Propofol on Cognitive Recovery After End of Study Drug TreatmentPropofolNo Delirium (CAM-ICU7 0-2)23Participants
Key Secondary: The Effect of Isoflurane vs Propofol on Cognitive Recovery After End of Study Drug TreatmentIsofluraneMild/Moderate Delirium (CAM-ICU7 3-5)9Participants
Key Secondary: The Effect of Isoflurane vs Propofol on Cognitive Recovery After End of Study Drug TreatmentPropofolMild/Moderate Delirium (CAM-ICU7 3-5)5Participants
Key Secondary: The Effect of Isoflurane vs Propofol on Cognitive Recovery After End of Study Drug TreatmentIsofluraneSevere Delirium (CAM-ICU7 6-7)12Participants
Key Secondary: The Effect of Isoflurane vs Propofol on Cognitive Recovery After End of Study Drug TreatmentPropofolSevere Delirium (CAM-ICU7 6-7)4Participants
Key Secondary: The Effect of Isoflurane vs Propofol on Spontaneous Breathing Effort During the Study Drug Treatment PeriodIsoflurane69.9Standard Deviation 38.28% of observations
Key Secondary: The Effect of Isoflurane vs Propofol on Spontaneous Breathing Effort During the Study Drug Treatment PeriodPropofol54.6Standard Deviation 39.25% of observations
Other Secondary: The Effect of Isoflurane vs Propofol on Time From Sedation Termination to Extubation in Patients for Whom Study Drug is Terminated for ExtubationIsoflurane67.5Inter-Quartile Range 17.5 to 1538.5Time to extubation (minutes)
Other Secondary: The Effect of Isoflurane vs Propofol on Time From Sedation Termination to Extubation in Patients for Whom Study Drug is Terminated for ExtubationPropofol80.0Inter-Quartile Range 14.0 to 1200.0Time to extubation (minutes)
Other Secondary: The Effect of Isoflurane vs Propofol on Days Alive and Free of Mechanical Ventilation Through Study Day 30Isoflurane19.695% Confidence Interval 17.17 to 22.10Days
Other Secondary: The Effect of Isoflurane vs Propofol on Days Alive and Free of Mechanical Ventilation Through Study Day 30Propofol19.895% Confidence Interval 17.02 to 22.55Days
Other Secondary: To Compare the Effect of Isoflurane vs Propofol on Days Alive and Free of the ICUIsoflurane12.595% Confidence Interval 10.12 to 14.86Days
Other Secondary: To Compare the Effect of Isoflurane vs Propofol on Days Alive and Free of the ICUPropofol12.195% Confidence Interval 9.40 to 14.67Days

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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