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Trial · NCT05344027

The Impact of Mitotane Therapy on Serum Free Proteins in Patients With Adrenocortical Carcinoma

NCT05344027, Completed, King's College Hospital NHS Trust

3 sourcestrials-2026-11-12-0.4.0

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ConductScience Library. The Impact of Mitotane Therapy on Serum Free Proteins in Patients With Adrenocortical Carcinoma. Trials, record NCT05344027. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05344027

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
The Impact of Mitotane Therapy on Serum Free Proteins in Patients With Adrenocortical Carcinoma
NCT number
NCT05344027
Status
Completed
Enrollment
35 participants, actual
Lead sponsor
King's College Hospital NHS Trust
Conditions
Adrenocortical Carcinoma
Interventions
Mitotane
First posted
2022-04-25
Last updated
2023-03-08

Source ClinicalTrials.gov

Registered outcomes1

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryExamine the effect of mitotane therapy on serum thyroid and cortisol binding proteins in patients with ACCApril 2019-June 2020
The primary objective of this project is to determine the effects of mitotane therapy on serum thyroid binding and cortisol binding protein concentrations in patients with adrenocortical carcinoma and compare concentrations of the same binding proteins in patients with adrenal neoplasms not on treatment with mitotane and to a cohort of pregnant women.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers15

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
1903011BACKGROUNDPubMed
16551738BACKGROUNDPubMed
18824557RESULTPubMed
19473175BACKGROUNDPubMed
19500769BACKGROUNDPubMed
21220434BACKGROUNDPubMed
22551107RESULTPubMed
23254310BACKGROUNDPubMed
23561851BACKGROUNDPubMed
24160811BACKGROUNDPubMed

1 to 10 of 15

See all 15 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Source

Release
trials-2026-11-12-0.4.0
Release manifest SHA-256
0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
Registry capture
2026-11-12
Results copy, AACT
2026-03-23
NIH clinical studies file
2026-11-13

Source ClinicalTrials.gov

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05344027

GET https://conductscience.org/api/trials/v1/NCT05344027/registered