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Trial · NCT05370794

Is in Vitro Maturation of Oocytes Influenced by the Origin of Gonadotropins Used in Maturation Medium: is There a Difference in Efficiency When Using Urinary Versus Recombinant Produced Follicle Stimulating Hormone and Human Chorionic Gonadotropin

NCT05370794, Unknown, Universitair Ziekenhuis Brussel

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Is in Vitro Maturation of Oocytes Influenced by the Origin of Gonadotropins Used in Maturation Medium: is There a Difference in Efficiency When Using Urinary Versus Recombinant Produced Follicle Stimulating Hormone and Human Chorionic Gonadotropin. Trials, record NCT05370794. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT05370794

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Is in Vitro Maturation of Oocytes Influenced by the Origin of Gonadotropins Used in Maturation Medium: is There a Difference in Efficiency When Using Urinary Versus Recombinant Produced Follicle Stimulating Hormone and Human Chorionic Gonadotropin
NCT number
NCT05370794
Status
Unknown
Enrollment
35 participants, estimated
Lead sponsor
Universitair Ziekenhuis Brussel
Conditions
In Vitro Maturation of Oocytes
Interventions
rhCG= Ovitrelle®, 250g/0.5ml = 26000IU/ml, Merck-Serono, rFSH = Gonal F®, 300IU/0.5ml, Merck-Serono
First posted
2022-05-12
Last updated
2022-11-07

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
Primaryoocyte maturationoocyte maturation is assessed after 30 hours of in vitro maturationthe ability of the oocyte to extrude the first polar body
SecondaryFertilization ratethe presence of 2 pronuclei is assessed between 18-20 hours after ICSIthe ability of the oocyte to ba activated and form pronuclei
Secondarymorphologic parameters describing embryo quality per fertilized oocyteembryo developmental assessment is performed 3 days after ICSI
embryo developmental potential as estimated by morphological characteristics: embryos with 6 cells or more, less than 20% fragmentation, cell size according to division pattern and the absence of multinucleated blastomeres are considered as good quality embryos. As secondary parameters, the presence of vacuoles or granulation in the majority of blastomeres will exclude the embryo from the 'good quality' group regardless of the earlier mentioned parameters.
Secondaryutilization rateutilization rate will be established 3 days after ICSIthe embryos of sufficient quality to be vitrified for a deferred embryo transfer

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers6

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
17524398BACKGROUNDPubMed
19778474BACKGROUNDPubMed
21072289BACKGROUNDPubMed
29044421BACKGROUNDPubMed
31111879BACKGROUNDPubMed
34050448BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT05370794

GET https://conductscience.org/api/trials/v1/NCT05370794/registered