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Trial · NCT05373134

Registered outcomes23

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in AaPO2 gradient by at least 5mmHg or to a value less than 15mm Hg at the end of 6 months from baseline6 months
SecondaryChange in grading of intrapulmonary shunting at the end of 3 month, from baseline as assessed by saline contrast echocardiography3 months
SecondaryChange in grading of intrapulmonary shunting at the end of 6 month, from baseline as assessed by saline contrast echocardiography6 months
SecondaryChange in DLCO (Diffusing Capacity of the lungs for Carbon Monoxide) at the end of 3 month from baseline3 month
SecondaryChange in Forced expiratory volume 1 (FEV1) at the end of 3 month from baseline3 month
SecondaryChange in FVC (Forced Vital Capacity) at the end of 3 month from baseline3 month
SecondaryChange in FEV1/FVC ratio at the end of 3 month from baseline3 month
SecondaryChange in 6-minute walk test at the end of 3 month from baseline3 month
SecondaryChange in DLCO (Diffusing Capacity of the lungs for Carbon Monoxide) at the end of 6 month from baseline6 month
SecondaryChange in Forced expiratory volume 1 (FEV1) at the end of 6 month from baseline6 month
SecondaryChange in FVC (Forced Vital Capacity) at the end of 6 month from baseline6 month
SecondaryChange in FEV1/FVC ratio at the end of 6 month from baseline6 month
SecondaryChange in 6-minute walk test at the end of 6 month from baseline6 month
SecondaryChange in seated oxygen saturation at 3 month from baseline3 month
SecondaryChange in PaO2 at 3 month from baseline3 month
SecondaryChange in seated oxygen saturation at 6 month from baseline6 month
SecondaryChange in PaO2 at 6 month from baseline6 month
SecondaryChange in inflammatory markers at the end of 3 month from baseline3 monthTNF alpha levels, vWF, ET-1, IL-6, S-1-P levels
SecondaryChange in inflammatory markers at the end of 6 month from baseline6 monthTNF alpha levels, vWF, ET-1, IL-6, S-1-P levels at the end of 6 month from baseline
SecondaryChange in inflammatory markers at the end of 3 month from baseline in a subset of patients wherever feasible3 monthVEGFR-3, iNOS, eNOS and IL-1 β

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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GET https://conductscience.org/api/trials/v1/NCT05373134/registered